van Wezel E M, de Bruijne J, Damman K, Bijmolen M, van den Berg A P, Verschuuren E A M, Ruigrok G A, Riezebos-Brilman A, Knoester M
Department of Clinical Microbiology and Infection Prevention, University of Groningen, University Medical Center Groningen, The Netherlands.
Department of Gastroenterology, University of Utrecht, Utrecht University Medical Center, The Netherlands.
Open Forum Infect Dis. 2019 Aug 1;6(8). doi: 10.1093/ofid/ofz346.
Ribavirin is effective for treating immunocompromised patients with chronic hepatitis E virus infection. However, ribavirin treatment is not always successful. We describe 3 solid organ transplant recipients treated with sofosbuvir and ribavirin after failing ribavirin monotherapy. Complete elimination of hepatitis E virus could not be achieved.
利巴韦林对治疗免疫功能低下的慢性戊型肝炎病毒感染患者有效。然而，利巴韦林治疗并非总是成功。我们描述了3例实体器官移植受者，在利巴韦林单药治疗失败后接受索磷布韦和利巴韦林治疗。戊型肝炎病毒未能完全清除。
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