年龄相关性白内障患者白内障手术和人工晶状体植入对视觉功能和生活质量的影响：系统评价方案。
Effects of cataract surgery and intra-ocular lens implantation on visual function and quality of life in age-related cataract patients: a systematic review protocol.
机构信息
Health Technology Assessment in India, Department of Health Research, Ministry of Health and Family Welfare, Indian Red Cross Society Building, 1, Red Cross Road, New Delhi, 110001, India.
Indian Council of Medical Research, (ICMR), New Delhi, India.
出版信息
Syst Rev. 2019 Aug 13;8(1):204. doi: 10.1186/s13643-019-1113-6.
BACKGROUND
Cataract is the leading cause of blindness and low vision worldwide. Presently, cataract surgery is the only treatment for cataract and is very effective in restoring sight. In cataract surgery, the natural lens of the eye that becomes clouded is removed and replaced with an artificial intraocular lens. There are multiple techniques for removal of lens as well as many types of intraocular lenses available for implantation. For this reason, it becomes imperative to monitor the impact of different surgical techniques and different intraocular lenses on health-related quality of life (HRQoL) of the patients. This systematic review aims to evaluate HRQoL evidences on effects of different types of cataract surgeries and intraocular lenses on visual function and quality of life in age-related cataract patients.
METHOD
Databases like Cochrane, EMBASE, SCOPUS, NHS Economic Evaluation Database (NHS EED), Health Technology Assessment (HTA) database, MEDLINE, ClinicalTrials.gov , Current Controlled Trials and World Health Organization International Clinical Trials Registry Platform (WHO ICTRP) will be searched systematically. Two reviewers will independently screen studies using predefined inclusion and exclusion criteria along with the extraction of data, and assessment of methodological quality using a standard checklist.
DISCUSSION
This systematic review will help in understanding how different types of cataract surgeries and intraocular lenses make a difference on quality of life of age-related cataract patients in terms of visual function and health-related quality of life. As the review attempts to bring together all the cataract-related HRQoL evidences pertaining to different cataract surgical techniques, different intraocular lenses and cataract-related complications, it will also identify gaps in evidence.
SYSTEMATIC REVIEW REGISTRATION
PROSPERO CRD42018092377.
背景
白内障是全球致盲和低视力的主要原因。目前，白内障手术是治疗白内障的唯一方法，对于恢复视力非常有效。在白内障手术中，会移除混浊的天然晶状体，并植入人工晶状体。有多种晶状体切除技术，也有多种类型的人工晶状体可供植入。因此，监测不同手术技术和不同人工晶状体对患者健康相关生活质量（HRQoL）的影响变得至关重要。本系统评价旨在评估不同类型的白内障手术和人工晶状体对年龄相关性白内障患者视觉功能和生活质量的 HRQoL 影响的证据。
方法
系统检索 Cochrane、EMBASE、SCOPUS、NHS 经济评价数据库（NHS EED）、卫生技术评估（HTA）数据库、MEDLINE、ClinicalTrials.gov、当前对照试验和世界卫生组织国际临床试验注册平台（WHO ICTRP）等数据库。两名审查员将根据预定义的纳入和排除标准，独立筛选研究，并使用标准清单提取数据和评估方法学质量。
讨论
本系统评价将有助于了解不同类型的白内障手术和人工晶状体如何在视觉功能和健康相关生活质量方面对年龄相关性白内障患者的生活质量产生影响。由于该评价试图汇集所有与白内障相关的 HRQoL 证据，涉及不同的白内障手术技术、不同的人工晶状体和白内障相关的并发症，因此也将确定证据中的空白。
系统评价注册
PROSPERO CRD42018092377。
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