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[长期使用贝特类药物治疗期间伴有肌溶解的非典型肌肉综合征]

[Atypical muscular syndrome with myolysis during long-term treatment with fibrates].

作者信息

Chauvin M, Zupan M, Brechenmacher C

机构信息

CMCO, Strasbourg.

出版信息

Arch Mal Coeur Vaiss. 1988 Jul;81(7):921-3.

PMID:3142389
Abstract

Acute inflammatory muscular syndromes secondary to clofibrate therapy are rare. They usually present with muscular pain in all four limbs with biochemical signs of rhabdomyolysis. The outcome is favourable as a rule with rapid regression of the clinical and biochemical changes after stopping the responsible drug. The authors report an atypical case of this syndrome with chest pains suggestive of angina.

摘要

氯贝丁酯治疗继发的急性炎症性肌肉综合征较为罕见。它们通常表现为四肢肌肉疼痛,并伴有横纹肌溶解的生化指标。通常情况下,停用相关药物后临床和生化变化迅速消退,预后良好。作者报告了该综合征的一个非典型病例,患者有提示心绞痛的胸痛症状。

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