研究肾脏氧合方法的又一进展。

Another step forward for methods for studying renal oxygenation.

机构信息

Cardiovascular Disease Program, Biomedicine Discovery Institute and Department of Physiology, Monash University, Melbourne, Australia.

出版信息

Kidney Int. 2019 Sep;96(3):552-554. doi: 10.1016/j.kint.2019.05.010.

DOI:10.1016/j.kint.2019.05.010

PMID:31445583

Abstract

All available methods for assessing renal oxygenation are limited either in terms of their temporal or spatial resolution, their ability to quantify tissue oxygen tension (PO), or in the settings in which they can be applied. Kodama and colleagues have developed a new method that utilizes dynamic nuclear polarization magnetic resonance imaging and an oxygen-sensitive paramagnetic agent (OX63). This new method generates quantitative maps of renal tissue PO in millimeters of mercury.

摘要

所有现有的评估肾脏氧合的方法在时间或空间分辨率、量化组织氧张力 (PO) 的能力，或在可应用的环境方面都存在局限性。Kodama 及其同事开发了一种新方法，该方法利用动态核极化磁共振成像和一种氧敏感顺磁剂 (OX63)。这种新方法可以生成毫米汞柱的肾脏组织 PO 定量图。