Gálvez-Caballero David, Huaringa-Marcelo Jorge, Conde-Vela César, Alarcón-Ruiz Christoper A, Fernández-Chinguel José Ernesto, Taype-Rondan Alvaro, Dyck-Arbulú Hector van, Espinoza-Rivas Gladys Martha, Morón-Castro Julio Alberto, Ortega-Díaz Jorge Luis, Rodríguez-Urteaga Zoila Ivonne, Timaná-Ruiz Raúl
Department of Clinical Cardiology, Instituto Nacional Cardiovascular (INCOR), EsSalud.
Clinical Practice Guidelines, Drug Safety Monitoring and Techno-surveillance Directorate, Institute for Health Technologies Evaluation and Research, EsSalud.
Arch Cardiol Mex. 2019;89(1):53-67. doi: 10.24875/ACME.M19000009.
This article summarizes the clinical practice guide (CPG) for the evaluation and management of patients with severe aortic stenosis in the Social Security of Peru (EsSalud).
To provide clinical evidence-based recommendations for the evaluation and management of patients with severe aortic stenosis in the EsSalud.
A local guideline development group (local GDG) was established, including medical specialists and methodologists. The local GDG formulated 7 clinical questions to be answered by this CPG. Systematic searches of systematic reviews and, when it was considered pertinent, primary studies, were conducted in PubMed during 2018. The evidence to answer each of the posed clinical questions was selected. The quality of the evidence was evaluated using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology. In periodic work meetings, the local GDG used the GRADE methodology to review the evidence and formulate the recommendations, points of good clinical practice, and the flowchart of evaluation and management. Finally, the CPG was approved with Resolution N.° 47 - IETSI - ESSALUD - 2018.
This CPG addressed 7 clinical questions regarding two issues: the initial evaluation and the management of severe aortic stenosis. Based on these questions, 9 recommendations (1 strong recommendation and 8 weak recommendations), 16 points of good clinical practice, and 1 flowchart were formulated.
This article summarizes the methodology and evidence-based conclusions from the CPG for the evaluation and management of patients with severe aortic stenosis in the EsSalud.
本文总结了秘鲁社会保障机构(EsSalud)中重度主动脉瓣狭窄患者评估与管理的临床实践指南(CPG)。
为EsSalud中重度主动脉瓣狭窄患者的评估与管理提供基于临床证据的建议。
成立了一个本地指南制定小组(本地GDG),成员包括医学专家和方法学家。本地GDG制定了7个临床问题,本CPG需回答这些问题。2018年期间在PubMed上对系统评价进行了系统检索,并在认为相关时检索了原始研究。选择了回答每个提出的临床问题的证据。使用推荐分级评估、制定和评价(GRADE)方法对证据质量进行评估。在定期工作会议上,本地GDG使用GRADE方法审查证据并制定建议、良好临床实践要点以及评估与管理流程图。最后,CPG经第47 - IETSI - ESSALUD - 2018号决议批准。
本CPG涉及关于两个问题的7个临床问题:重度主动脉瓣狭窄的初始评估和管理。基于这些问题,制定了9条建议(1条强烈推荐和8条弱推荐)、16个良好临床实践要点以及1个流程图。
本文总结了EsSalud中重度主动脉瓣狭窄患者评估与管理CPG的方法和基于证据的结论。