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正念与术后疼痛的关联:行微创子宫切除术的妇科肿瘤患者的前瞻性队列研究。

The Association Between Mindfulness and Postoperative Pain: A Prospective Cohort Study of Gynecologic Oncology Patients Undergoing Minimally Invasive Hysterectomy.

机构信息

Brown University/Women and Infants Hospital of Rhode Island, Providence (all authors); Johns Hopkins School of Medicine, Baltimore, Maryland (Dr. Weston).

Brown University/Women and Infants Hospital of Rhode Island, Providence (all authors).

出版信息

J Minim Invasive Gynecol. 2020 Jul-Aug;27(5):1119-1126.e2. doi: 10.1016/j.jmig.2019.08.021. Epub 2019 Aug 23.

DOI:10.1016/j.jmig.2019.08.021
PMID:31449907
Abstract

STUDY OBJECTIVE

To describe the association between preoperative dispositional mindfulness (the personality trait of being mindful) and postoperative pain in gynecologic oncology patients undergoing minimally invasive hysterectomy.

DESIGN

Prospective cohort study.

SETTING

University-affiliated teaching hospital.

PATIENTS

Gynecologic oncology patients (n = 126) planning minimally invasive hysterectomy.

INTERVENTIONS

Minimally invasive hysterectomy.

MEASUREMENTS AND MAIN RESULTS

Baseline mindfulness was assessed at the preoperative visit using the Five Facet Mindfulness Questionnaire (FFMQ). Postoperative pain and opioid usage were evaluated via chart review and surveys at postoperative visits at 1 to 2 weeks and 4 to 6 weeks. Higher baseline mindfulness was correlated with lower postoperative pain as measured by both the average and highest numeric pain scores during the inpatient stay (r = -.23, p = .020; r = -.21, p = .034). At the initial postoperative visit, pain score was also inversely correlated with preoperative mindfulness score (r = -.26, p = .008). This relationship was not observed at the final postoperative visit (r = -.08, p = .406). Pre-operative mindfulness and opioid usage were also inversely associated, though this relationship did not reach statistical significance (r = -.18, p = .066).

CONCLUSION

Mindfulness was previously shown to be a promising intervention for chronic pain treatment. Our study demonstrates that higher preoperative dispositional mindfulness is associated with more favorable postoperative pain outcomes, including lower pain scores but not lower opioid consumption. This relationship provides an opportunity to target the modifiable personality characteristic of mindfulness, to reduce postoperative pain in patients following gynecologic surgery.

摘要

研究目的

描述术前性格特质正念(注意当下的特质)与行微创子宫切除术的妇科肿瘤患者术后疼痛之间的关联。

设计

前瞻性队列研究。

地点

大学附属教学医院。

患者

计划行微创子宫切除术的妇科肿瘤患者(n=126)。

干预措施

微创子宫切除术。

测量和主要结果

在术前就诊时,使用五因素正念量表(FFMQ)评估基线正念水平。通过图表回顾和术后 1 至 2 周和 4 至 6 周的调查评估术后疼痛和阿片类药物使用情况。基线正念水平越高,住院期间平均和最高数字疼痛评分的术后疼痛越低(r=-.23,p=.020;r=-.21,p=.034)。在最初的术后就诊时,疼痛评分与术前正念评分也呈负相关(r=-.26,p=.008)。但在最后一次术后就诊时,未观察到这种相关性(r=-.08,p=.406)。术前正念和阿片类药物使用也呈负相关,但未达到统计学意义(r=-.18,p=.066)。

结论

正念先前被证明是治疗慢性疼痛的一种有前途的干预措施。我们的研究表明,较高的术前性格特质正念与更有利的术后疼痛结果相关,包括较低的疼痛评分,但不包括较低的阿片类药物使用量。这种关系为针对正念这一可改变的人格特征,减少妇科手术后患者的术后疼痛提供了机会。

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