Jarujamrus Purim, Meelapsom Rattapol, Naksen Puttharaksa, Ditcharoen Nadh, Anutrasakda Wipark, Siripinyanond Atitaya, Amatatongchai Maliwan, Supasorn Saksri
Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Ubon Ratchathani University, Ubon Ratchathani, 34190, Thailand; Nanomaterials Science, Sensors & Catalysis for Problem-Based Projects, Faculty of Science, Ubon Ratchathani University, Ubon Ratchathani, 34190, Thailand.
Nanomaterials Science, Sensors & Catalysis for Problem-Based Projects, Faculty of Science, Ubon Ratchathani University, Ubon Ratchathani, 34190, Thailand; Department of Science and Mathematics, Faculty of Science and Health Technology, Kalasin University, Kalasin, 46000, Thailand.
Anal Chim Acta. 2019 Nov 15;1082:66-77. doi: 10.1016/j.aca.2019.06.058. Epub 2019 Jul 9.
This work reports the first use of cis-1,4-polyisoprene obtained from rubber latex (RL) waste as the hydrophobic reagent for the fabrication of a microfluidic paper-based analytical device (μPAD), providing a user-friendly means for magnesium detection. The μPAD was fabricated using a screen printing technique and the barcode-like paper sensor was then used for the detection of Mg(II) ions in RL and water samples. Using different types of paper media (paper towel, Whatman No.1 and Whatman No.4), the results indicate that the key factors in optimizing the quality of the fabricated μPAD include the viscosity of cis-1,4-polyisoprene solution which could be adjusted using different solvents and heating temperatures, the mesh screen size, the pore size of the paper substrates, and the dimension of the sample zone. The fabricated μPAD, which showed high chemical resistance, durability and design flexibility, was tested for the detection of Mg(II) ions using the reaction based on complexometric titration with EDTA where Eriochrome Black T was used as an indicator. An Android application "UBU OMg Sensor" was also developed to provide a simple, fast, and accurate means for end-users to interpret results generated by our developed μPAD.
这项工作报道了首次将从橡胶胶乳（RL）废料中获得的顺式-1,4-聚异戊二烯用作制造微流控纸基分析装置（μPAD）的疏水试剂，为镁检测提供了一种用户友好的方法。μPAD采用丝网印刷技术制造，然后将条形码状的纸质传感器用于检测RL和水样中的Mg(II)离子。使用不同类型的纸张介质（纸巾、Whatman No.1和Whatman No.4），结果表明，优化制造的μPAD质量的关键因素包括顺式-1,4-聚异戊二烯溶液的粘度（可使用不同溶剂和加热温度进行调节）、筛网尺寸、纸质基材的孔径以及样品区的尺寸。制造的μPAD具有高耐化学性、耐久性和设计灵活性，基于用乙二胺四乙酸（EDTA）进行络合滴定并以铬黑T作为指示剂的反应，对其进行了Mg(II)离子检测测试。还开发了一个安卓应用程序“UBU OMg Sensor”，为终端用户提供一种简单、快速且准确的方法来解读我们开发的μPAD产生的结果。
