Atik Bülent, Kılınç Gökhan, Atsal Abdullah Ömer, Çöken Fuat, Yarar Volkan
Atatürk City Hospital, Department of Anesthesiology and Reanimation, Balikesir, Turkey.
Atatürk City Hospital, Department of Anesthesiology and Reanimation, Balikesir, Turkey.
Transplant Proc. 2019 Sep;51(7):2183-2185. doi: 10.1016/j.transproceed.2019.01.148.
Nowadays, as the number of patients waiting for organ transplant is increasing, it is important to diagnose brain death in intensive care units and to provide good donor care. We aimed to share our experience of donor care with the diagnosis of brain death in our clinic.
One hundred and fifty-one patients diagnosed in our clinic with brain death between June 2006 to 2018 were studied retrospectively.
The mean age of the 151 patients was 46.6 (1-89) years. Fifty-seven (37.7%) of the 151 patients' families accepted donation. Ten out of 57 patients could not be organ donors for medical reasons. Eighty-four kidneys, 7 hearts, and 40 livers were transplanted to the patients. When the diagnosis at admission to the intensive care unit was examined, it was found that the most common diagnosis was intracranial hemorrhage (36.8%), followed by head trauma (21.05%), drowning in water (3.5%), and firearm injury (3.5%). The apnea test was applied to all cases, but 17 patients could not complete the apnea test. In order to support the diagnosis of brain death, in 63% of patients (n = 95) radiological methods were performed. Cranial computed tomography angiography was performed as a radiological method. All cases were found to have received at least 1 inotropic support. We used dopamine in 41 patients, noradrenaline in 36 patients, dobutamine in 8 patients, and adrenaline in 3 patients. During the 12 months when the organ transplant coordinator was not on duty, there were no organ donors. It is important to maintain an organ and tissue transplant coordinator and an intensive care unit team for organ donation.
In order to increase the cadaver donor pool, it is necessary to increase the number of brain death diagnoses and decrease the rate of family rejection. Therefore, patients with poor neurologic prognosis should be carefully monitored for brain death. Successful family discussions by an experienced and trained organ transplant coordinator should try to increase donation rates by emphasizing the importance of organ donation and the fact that brain death is a real death.
如今,随着等待器官移植患者数量的增加,在重症监护病房诊断脑死亡并提供良好的供体护理至关重要。我们旨在分享我们诊所脑死亡诊断中供体护理的经验。
回顾性研究了2006年6月至2018年期间在我们诊所诊断为脑死亡的151例患者。
151例患者的平均年龄为46.6(1 - 89)岁。151例患者中57例(37.7%)的家属接受了捐赠。57例患者中有10例因医学原因无法成为器官供体。84个肾脏、7颗心脏和40个肝脏被移植给了患者。检查重症监护病房入院时的诊断发现,最常见的诊断是颅内出血(36.8%),其次是头部外伤(21.05%)、溺水(3.5%)和火器伤(3.5%)。所有病例均进行了 apnea 试验,但17例患者未能完成 apnea 试验。为支持脑死亡诊断,63%的患者(n = 95)进行了放射学检查。作为放射学检查方法进行了头颅计算机断层血管造影。所有病例均至少接受了1种血管活性药物支持。我们在41例患者中使用了多巴胺,36例患者中使用了去甲肾上腺素,8例患者中使用了多巴酚丁胺,3例患者中使用了肾上腺素。在器官移植协调员不在岗的12个月期间,没有器官供体。维持器官和组织移植协调员以及重症监护病房团队对于器官捐赠很重要。
为了增加尸体供体库,有必要增加脑死亡诊断数量并降低家属拒绝率。因此,对神经预后不良的患者应仔细监测脑死亡情况。经验丰富且经过培训的器官移植协调员进行成功的家属讨论,应通过强调器官捐赠的重要性以及脑死亡是真正死亡这一事实来努力提高捐赠率。