美国强直性脊柱炎的临床特征和合并症的种族差异。
Racial Differences in Clinical Features and Comorbidities in Ankylosing Spondylitis in the United States.
机构信息
From Case Western Reserve University, MetroHealth Medical Center, Cleveland, Ohio, USA.
D.K. Singh, MD, Case Western Reserve University, MetroHealth Medical Center; M.N. Magrey, MD, Case Western Reserve University, MetroHealth Medical Center.
出版信息
J Rheumatol. 2020 Jun 1;47(6):835-838. doi: 10.3899/jrheum.181019. Epub 2019 Sep 1.
OBJECTIVE
To examine racial differences of clinical features, medication usage, and comorbidities of patients with ankylosing spondylitis (AS) in the United States.
METHODS
In the Explorys database, 28,520 patients with AS were identified. Data were stratified by 2 rheumatology visits, race, sex, clinical characteristics, medication use, and comorbidities. Datasets were recorded as proportions, which were compared using chi-square test (p < 0.05).
RESULTS
Of the 10,990 patients with AS, 8% were African Americans and had elevated erythrocyte sedimentation rate and C-reactive protein, and high frequency of anterior uveitis, hypertension, diabetes, depression, and heart disease.
CONCLUSION
African Americans with AS in the United States have high disease activity and comorbidities compared to whites.
目的
研究美国强直性脊柱炎（AS）患者的临床特征、药物使用和合并症的种族差异。
方法
在 Explorys 数据库中，确定了 28520 例 AS 患者。根据 2 次风湿病就诊、种族、性别、临床特征、药物使用和合并症对数据进行分层。数据集以比例表示，使用卡方检验（p<0.05）进行比较。
结果
在 10990 例 AS 患者中，8%为非裔美国人，红细胞沉降率和 C 反应蛋白升高，前葡萄膜炎、高血压、糖尿病、抑郁和心脏病的发生率较高。
结论
与白人相比，美国的非裔 AS 患者疾病活动度和合并症更高。
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