伊朗学童的不同角膜地形模式分布：沙赫鲁德学童眼队列研究。

Distribution of Different Corneal Topography Patterns in Iranian Schoolchildren: The Shahroud Schoolchildren Eye Cohort Study.

机构信息

Noor Research Center for Ophthalmic Epidemiology (H.H.), Noor Eye Hospital, Tehran, Iran; Noor Ophthalmology Research Center (R.P.), Noor Eye Hospital, Tehran, Iran; Department of Medical Surgical Nursing (M.K.), School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Refractive Errors Research Center (A.Y.), Mashhad University of Medical Sciences, Mashhad, Iran; Ophthalmic Epidemiology Research Center (M.H.E.), Shahroud University of Medical Sciences, Shahroud, Iran; and Department of Epidemiology and Biostatistics (A.F.), School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Eye Contact Lens. 2020 May;46(3):154-159. doi: 10.1097/ICL.0000000000000652.

DOI:10.1097/ICL.0000000000000652

PMID:31490850

Abstract

OBJECTIVES

To determine the distribution of corneal topography patterns (CTPs) in children aged 6 to 12 years and its association with the central corneal thickness (CCT), axial length (AL), mean corneal power (MCP), and corneal astigmatism (CA).

METHODS

In this population-based study, 5,620 children selected through random stratified cluster sampling were examined. After applying the inclusion criteria, 4,655 right eyes were analyzed. The Pentacam was used to determine the CTP and measure CA and MCP, and the BioGraph was used to measure the AL. Corneal topography patterns were classified based on the 10 patterns proposed by Rabinowitz et al. RESULTS:: The most common pattern in the right eye was the oval pattern [32.7%, 95% confidence interval (CI): 30.9-34.5] followed by asymmetric bowtie with superior steepening (AB-SS) (14.5%, 95% CI: 13.3-15.7), whereas the rarest patterns were AB with skewed radial axis (AB-SRAX) (0.1%, 95% CI: 0.0-0.2) and irregular pattern (0.2%, 95% CI: 0.1-0.4). The similarity between the two eyes was 23.2% (95% CI: 20.9-25.7). The mean CCT was significantly higher in AB-SS than inferior steepening (IS) (P=0.023), symmetric bowtie with SRAX (SB-SRAX) (P=0.030), and AB with IS (AB-IS) (P=0.015). Corneal astigmatism was higher in SB-SRAX compared with round and oval patterns (P value for both <0.001). The AL was greater, and the MCP was lower in the oval versus the SB-SRAX pattern (P value for both <0.001).

CONCLUSION

The distribution of CTP was different in children and adults, and the oval and AB-SS patterns were the most common CTPs in the current study.

摘要

目的

确定 6 至 12 岁儿童的角膜地形模式（CTP）分布及其与中央角膜厚度（CCT）、眼轴（AL）、平均角膜屈光力（MCP）和角膜散光（CA）的关系。

方法

本研究为基于人群的研究，通过随机分层聚类抽样选择了 5620 名儿童，在应用纳入标准后，分析了 4655 只右眼。使用 Pentacam 确定 CTP 并测量 CA 和 MCP，使用 BioGraph 测量 AL。根据 Rabinowitz 等人提出的 10 种模式对角膜地形图模式进行分类。

结果

右眼最常见的模式是椭圆形模式[32.7%，95%置信区间（CI）：30.9-34.5]，其次是上陡变不对称蝶形（AB-SS）（14.5%，95%CI：13.3-15.7），而最罕见的模式是具有偏斜放射轴的 AB（AB-SRAX）（0.1%，95%CI：0.0-0.2）和不规则模式（0.2%，95%CI：0.1-0.4）。双眼之间的相似性为 23.2%（95%CI：20.9-25.7）。AB-SS 的平均 CCT 明显高于下陡变（IS）（P=0.023）、具有 SRAX 的对称蝶形（SB-SRAX）（P=0.030）和具有 IS 的 AB（AB-IS）（P=0.015）。与圆形和椭圆形模式相比，SB-SRAX 的角膜散光更高（两者的 P 值均<0.001）。与 SB-SRAX 模式相比，椭圆形的 AL 更大，MCP 更低（两者的 P 值均<0.001）。