Department of Medical Radiation Physics and Nuclear Medicine, Karolinska University Hospital, SE-171 76 Stockholm, Sweden. Department of Oncology-Pathology, Karolinska Institutet, SE-171 76 Stockholm, Sweden.
Phys Med Biol. 2019 Oct 21;64(20):205019. doi: 10.1088/1361-6560/ab421d.
Following the publication of the ICRU Report 90 (2016) on key data for measurement standards in radiation dosimetry, where ionometric air-kerma standards for kilovoltage (kV) x-ray beams are estimated to change by up to about 0.5%, an update of the backscatter factors and water/air ratios of mass energy-absorption coefficients in kV dosimetry protocols was deemed necessary for consistency through the entire dosimetry chain. In addition, numerical methods and Monte Carlo (MC) systems that did not exist at the time when air-kerma protocols were developed, are currently available. Calculations of the chamber-independent quantities required for the dosimetry of low- and medium-energy kV x rays were carried out using a consistent set of key data throughout the complete process. The quantities were based on MC calculations of a database for a dense grid of monoenergetic photons for different beam diameters and source-to-surface distances, followed by an averaging procedure to compute water/air energy-absorption coefficient ratios and backscatter factors for 342 experimental and calculated kV spectra. It was found that for a given HVL and field size the variation of backscatter factors for different kVs can be up to about 5%, a trend confirmed with independent calculations that shows the limitation of using only the HVL for the beam quality specification of kV x rays. Extensive tables as a function of beam quality in terms of kV and HVL were developed for configurations that might be encountered in clinical practice; the data are also available in the form of a GUI web app at http://52.233.195.208. Results were compared with data used at PTB for deriving low-energy [Formula: see text] ion chamber calibration coefficients, finding agreement within about [Formula: see text]0.5%, and with independent full MC kerma calculations that agreed within better than about 1%. Compared with the data in the AAPM TG-61 protocol (Ma et al 2001 Med. Phys. 28 868-93) there was in general good agreement for the ratios of mass energy-absorption coefficients, although differences of up to 1.5% resulted when both kV and HVL were taken into account; more significant discrepancies, within about 2%-6%, were obtained for backscatter factors, the present values being generally higher.
继《ICRU 报告 90(2016)》发布后,该报告对辐射剂量学中的关键数据测量标准进行了阐述,其中估计千伏(kV)X 射线束的离子辐射空气比释动能标准将发生高达约 0.5%的变化。因此,有必要更新整个剂量学链中,kV 剂量学协议中的反向散射因子和水/空气质量能量吸收系数比。此外,目前可使用当时制定空气比释动能协议时不存在的数值方法和蒙特卡罗(MC)系统。使用整个过程中一致的关键数据组,对用于低能和中能 kV X 射线剂量学的腔室独立量进行了计算。这些量是基于对不同束径和源皮距的密集单能光子数据库的 MC 计算得出的,然后通过平均程序计算 342 个实验和计算的 kV 光谱的水/空气能量吸收系数比和反向散射因子。结果表明,对于给定的 HVL 和射野大小,不同 kV 的反向散射因子的变化可达约 5%,这一趋势与独立计算结果一致,表明仅使用 HVL 来指定 kV X 射线的束质规格存在局限性。针对临床实践中可能遇到的配置,制定了以 kV 和 HVL 为参数的广泛表格;还可以以图形用户界面(GUI)网络应用程序的形式在 http://52.233.195.208 上获得数据。将结果与用于推导低能[Formula: see text]离子室校准系数的 PTB 数据进行了比较,发现两者之间的差异在约[Formula: see text]0.5%以内,与独立的全 MC 比释动能计算结果一致,后者的差异在 1%以内。与 AAPM TG-61 协议(Ma 等人,2001 年,《医学物理学》28 868-93)中的数据相比,质量能量吸收系数比的总体一致性较好,尽管同时考虑 kV 和 HVL 时会导致差异高达 1.5%;反向散射因子的差异更大,在 2%-6%左右,目前的值普遍较高。