DiMario F J, Clancy R R
Division of Neurology, Children's Hospital of Philadelphia, Pennsylvania.
Pediatr Neurol. 1988 Jul-Aug;4(4):249-51. doi: 10.1016/0887-8994(88)90040-9.
A 10-year-old girl with Lennox-Gastaut syndrome who received intravenous lorazepam for atypical absence status seizures is reported. Tonic seizures occurred immediately and appeared to represent a paradoxical seizure exacerbation. We also review other patients with paradoxical seizure exacerbation by benzodiazepines.