Dipartimento di Scienze Biomediche e Neuromotorie, Università di Bologna, Bologna, Italy.
IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Sleep Breath. 2019 Dec;23(4):1309-1314. doi: 10.1007/s11325-019-01937-w. Epub 2019 Sep 14.
Disorders of arousal include confusional arousals, sleepwalking and sleep terrors. The diagnosis of disorders of arousal is based on the clinical criteria established in the International Classification of Sleep Disorders, third edition, although the interobserver reliability of these criteria has never been investigated. The aim of this study was to estimate the inter-rater reliability of the diagnostic criteria for disorders of arousal throughout the whole life in order to understand their feasibility in clinical daily activity and in multicenter observational studies.
Three raters interviewed 126 subjects (patients complaining of sleep disorders, headache, and healthy subjects), aged 18-80 years, with a standardized questionnaire created by applying the International Diagnostic Criteria for Disorders of Arousal.
An "almost perfect" inter-rater reliability for disorders of arousal criteria and the final diagnosis was found among the raters (kappa 0.89 for confusional arousals, 0.87 for sleepwalking, and 0.87 for sleep terrors).
The International Classification of Sleep Disorders, Third Edition criteria are adequate for a reliable diagnosis of disorders of arousal. Further validation studies, confirming DOA diagnosis with video polysomnography, are needed to investigate the predictive value of ICSD-3 criteria.
觉醒障碍包括意识模糊性觉醒、梦游和睡惊。觉醒障碍的诊断基于《国际睡眠障碍分类》第三版中确立的临床标准,尽管这些标准的观察者间信度从未被研究过。本研究旨在评估觉醒障碍整个生命周期的诊断标准的观察者间信度,以了解其在临床日常活动和多中心观察性研究中的可行性。
3 名评估者使用由觉醒障碍国际诊断标准应用的标准化问卷,对 126 名年龄在 18-80 岁的受试者(主诉睡眠障碍、头痛的患者和健康受试者)进行了访谈。
评估者之间发现觉醒障碍标准和最终诊断具有“几乎完美”的观察者间信度(意识模糊性觉醒的kappa 值为 0.89,梦游为 0.87,睡惊为 0.87)。
《国际睡眠障碍分类》第三版标准可用于可靠诊断觉醒障碍。需要进一步的验证研究,使用视频多导睡眠图确认 DOA 诊断,以研究 ICSD-3 标准的预测价值。