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评估抗生素外科预防指南的可实施性。

Evaluating the implementability of Antibiotic Surgical Prophylaxis guidelines.

作者信息

Ierano Courtney, Ayton Darshini, Peel Trisha, Marshall Caroline, Thursky Karin

机构信息

National Health and Medical Research Council Centre of Research Excellence: National Centre for Antimicrobial Stewardship (NCAS), Peter Doherty Research Institute for Infection and Immunity Melbourne, VIC, Australia; University of Melbourne, Faculty of Medicine, Dentistry and Health Sciences, Department of Medicine, Royal Melbourne Hospital, Parkville, VIC, Australia.

Monash University, Department of Epidemiology and Preventive Medicine, 553 St Kilda Road, Melbourne, VIC, Australia.

出版信息

Infect Dis Health. 2020 Feb;25(1):11-21. doi: 10.1016/j.idh.2019.08.004. Epub 2019 Sep 12.

Abstract

BACKGROUND

Current Australian data highlight guideline noncompliant prescribing of antimicrobials for surgical prophylaxis. The study aim was to evaluate the implementability of the Australian national surgical prophylaxis (SAP) guidelines to identify facilitators for and barriers to compliance.

METHODS

Key stakeholders appraised the surgical prophylaxis guidelines using the GuideLine Implementability Appraisal (GLIA) tool. Questions with 100% agreement for the response 'Yes' were identified as facilitators and those with 100% agreement for 'No', a barrier. Questions that did not receive 100% agreement, but had a majority (40-60%) 'Yes' or 'No' consensus were considered as borderline facilitators and barriers respectively.

RESULTS

Ten appraisals were completed. Guideline recommendations were rated as easily identifiable and concise and were thus facilitators for implementation. The ability to measure guideline adherence and outcomes, and recommendations that were consistent with guideline user abilities and beliefs were also identified as facilitators. Borderline facilitators related to the clarity of the recommendations and whether they were explicit in what to do and in what circumstances. Evidence quality underpinning recommendations (validity), inflexibility of recommendations (flexibility) and the lack of patient data at the point of use (computability) were identified as borderline barriers to implementation. No recommendation reached agreement as being a barrier.

CONCLUSION

The GLIA appraisal demonstrated overall implementability of the current Australian national surgical prophylaxis guidelines. Facilitators (i.e., measurability) and borderline facilitators highlight strengths of the current guideline. Borderline barriers (i.e., validity, flexibility and computability) may negatively impact upon implementability. Guideline developers should consider these dimensions to optimise guideline uptake and consequently patient care.

摘要

背景

澳大利亚当前的数据突出显示了手术预防性使用抗菌药物时不符合指南的处方情况。本研究的目的是评估澳大利亚国家手术预防(SAP)指南的可实施性,以确定依从性的促进因素和障碍。

方法

关键利益相关者使用指南可实施性评估(GLIA)工具对手术预防指南进行评估。对于回答“是”达成100%共识的问题被确定为促进因素,而对于回答“否”达成100%共识的问题则为障碍。未达成100%共识,但有多数(40 - 60%)“是”或“否”共识的问题分别被视为临界促进因素和临界障碍。

结果

完成了十次评估。指南建议被评为易于识别且简洁,因此是实施的促进因素。能够衡量指南依从性和结果,以及与指南使用者能力和信念一致的建议也被确定为促进因素。临界促进因素与建议的清晰度以及它们在做什么和在何种情况下是否明确有关。支持建议的证据质量(有效性)、建议的不灵活性(灵活性)以及使用时缺乏患者数据(可计算性)被确定为实施的临界障碍。没有建议被一致认为是障碍。

结论

GLIA评估表明当前澳大利亚国家手术预防指南总体上具有可实施性。促进因素(即可衡量性)和临界促进因素突出了当前指南的优势。临界障碍(即有效性、灵活性和可计算性)可能会对可实施性产生负面影响。指南制定者应考虑这些方面以优化指南的采用率,从而改善患者护理。

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