[中性粒细胞胞外诱捕网在肿瘤转移中的研究进展]
[Research Progress of Neutrophil Extracellular Traps in Tumor Metastasis].
作者信息
Zhang Xinwei, Wang Yong, Li Yong
机构信息
Department of Medical Oncology, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Department of Medical Oncology, Ganzhou People's Hospital, Ganzhou 341000, China.
出版信息
Zhongguo Fei Ai Za Zhi. 2019 Sep 20;22(9):600-604. doi: 10.3779/j.issn.1009-3419.2019.09.08.
Recently, studies showed that neutrophils extracellular traps (NETs) are the fiber network structures formed by the materials released by neutrophils under various appropriate stimulation. NETs have been indicated to trap and kill microorganisms, playing a critical role in immune responses. It was pointed out that NETs can not only be involved in inflammation and thrombosis, but also is intimately related to tumor metastasis. Therefore, the study of NETs in tumor metastasis is of great significance for tumor therapy and the progress of NETs in tumor metastasis and the relevant mechanisms is summarized. .
最近，研究表明中性粒细胞胞外陷阱（NETs）是中性粒细胞在各种适当刺激下释放的物质形成的纤维网络结构。NETs已被证明可捕获并杀死微生物，在免疫反应中起关键作用。有人指出，NETs不仅可参与炎症和血栓形成，还与肿瘤转移密切相关。因此，研究NETs在肿瘤转移中的作用对肿瘤治疗具有重要意义，本文对NETs在肿瘤转移中的研究进展及相关机制进行综述。
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