Mardani Ahmad, Keshavarz Hossein
Department of Microbiology, Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran.
Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Iran J Parasitol. 2019 Apr-Jun;14(2):326-333.
Malaria is one of the most important transfusion-transmitted infections (TTIs) worldwide. To prevent the occurrence of transfusion-transmitted malaria (TTM), potential blood donors with a history of malaria or travel to, or residence in, malarious areas are permanently or temporarily deferred from donating blood. The objective of the present study was to evaluate the blood donor deferrals for malaria in Iran.
This descriptive cross-sectional study was conducted in the Iranian Blood Transfusion Organization (IBTO) from 21 Mar 2011 to 19 Mar 2016 (5 yr). The data were collected and extracted from IBTO comprehensive database, namely Negareh, and then recorded in a structured template form. Statistical analysis was performed using SPSS.
Of the 12,790,859 blood donation volunteers, 23,084 (0.18%) were deferred due to the risk of malaria. More than 90% of malaria-deferrals were because of travel to and residence in malaria endemic areas. Among the malaria-deferred volunteers, 22,139 (95.91%) were male and 945 (4.09%) were female; 2,053 (8.89%) were permanently deferred, while 21,031 (91.11%) were temporarily deferred. The highest malaria-deferral rates were observed in South Khorasan (0.82%), Razavi Khorasan (0.79%) and Yazd (0.54%) provinces, respectively.
Given the prevalence of malaria in neighboring countries (Pakistan and Afghanistan) and several provinces of Iran and the increasing human migration and movement between malaria non-endemic and endemic areas, the malaria-deferral rate might be higher than 0.18% in Iran. Thus, the changing, as well as the precise and accurate implementation of donor selection process must be considered in all blood transfusion centers of Iran.
疟疾是全球最重要的输血传播感染之一。为预防输血传播疟疾（TTM）的发生，有疟疾病史或前往疟疾流行地区旅行或居住的潜在献血者会被永久或暂时推迟献血。本研究的目的是评估伊朗因疟疾而推迟献血者的情况。
这项描述性横断面研究于2011年3月21日至2016年3月19日（5年）在伊朗输血组织（IBTO）进行。数据从IBTO的综合数据库Negareh中收集和提取，然后以结构化模板形式记录。使用SPSS进行统计分析。
在12,790,859名献血志愿者中，有23,084人（0.18%）因疟疾风险而被推迟献血。超过90%的疟疾推迟献血是因为前往疟疾流行地区旅行和居住。在因疟疾而推迟献血的志愿者中，22,139人（95.91%）为男性，945人（4.09%）为女性；2,053人（8.89%）被永久推迟，而21,031人（91.11%）被暂时推迟。最高的疟疾推迟献血率分别出现在霍拉桑省南部（0.82%）、拉扎维霍拉桑省（0.79%）和亚兹德省（0.54%）。
鉴于邻国（巴基斯坦和阿富汗）以及伊朗几个省份疟疾的流行情况，以及疟疾非流行区和流行区之间人类迁移和流动的增加，伊朗的疟疾推迟献血率可能高于0.18%。因此，伊朗所有输血中心都必须考虑献血者选择过程的变化以及精确和准确的实施。
