Peterson Andrea M, Brown Amy, Savage Ashlyn, Dempsey Angela
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Department of Obstetrics and Gynecology, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
Eur J Contracept Reprod Health Care. 2019 Dec;24(6):475-479. doi: 10.1080/13625187.2019.1666361. Epub 2019 Sep 23.
To characterise the frequency of and predictors of contraceptive implant discontinuation within 12 months of insertion in our clinical setting. This retrospective cohort study included women receiving the etonogestrel contraceptive implant at our hospital between May 2007 and May 2012. We abstracted data from charts including implant removal date, bleeding complaints, reproductive and demographic characteristics, prior contraceptive use, tobacco use and implant insertion timing. Our primary outcome was implant discontinuation within 12 months following insertion. SAS 9.4 (SAS Institute Inc., Cary, NC, USA) was used to generate frequencies, bivariate analyses and multivariate logistic regression models. Implant discontinuation was documented in 16% of implant users prior to 12 months (89/544). Women with documented bleeding complaints in the medical record were more likely to discontinue within 12 months (OR: 4.36, CI: 2.71, 7.00). No other demographic or clinical characteristics were associated with premature discontinuation. Having less than two prior pregnancies and tobacco use were associated with documented bleeding complaints. Discontinuation of the implant is associated with bleeding complaints. Women with lower parity and tobacco users may be more likely to experience bleeding or to find it intolerable.
为了描述在我们的临床环境中,避孕植入物在插入后12个月内取出的频率及预测因素。这项回顾性队列研究纳入了2007年5月至2012年5月期间在我院接受依托孕烯避孕植入物的女性。我们从病历中提取了数据,包括植入物取出日期、出血相关主诉、生殖和人口统计学特征、既往避孕方法使用情况、吸烟情况以及植入物插入时间。我们的主要结局是植入后12个月内取出植入物。使用SAS 9.4(美国北卡罗来纳州卡里市SAS研究所)生成频率、双变量分析和多变量逻辑回归模型。16%的植入物使用者在12个月前取出了植入物(89/544)。病历中有出血相关主诉记录的女性在12个月内取出植入物的可能性更大(比值比:4.36,可信区间:2.71,7.00)。没有其他人口统计学或临床特征与过早取出相关。既往妊娠次数少于两次和吸烟与有出血相关主诉记录有关。取出植入物与出血相关主诉有关。低生育次数的女性和吸烟者可能更易出现出血或觉得难以耐受。