Department of Obstetrics and Gynaecology, Monash University, Clayton, Victoria, Australia.
Department of Obstetrics and Gynaecology, Monash University, Clayton, Victoria, Australia; Monash Women's, Monash Health, Clayton, Victoria, Australia.
Pregnancy Hypertens. 2019 Oct;18:67-74. doi: 10.1016/j.preghy.2019.09.005. Epub 2019 Sep 20.
In recent years, there has been an increasing amount of information published on pre-eclampsia. We analyzed trends in pre-eclampsia literature between 1997 and 2016 and reported on the quality and utility of randomized controlled trials (RCTs) between 1987 and 2016.
We searched PubMed for all articles containing "pre-eclampsia" or "hypertensive disorders of pregnancy" in the title between 1997 and 2016 for the general literature and between 1987 and 2016 for RCTs. An analysis was performed based on study type, languages and publications from high-impact journals. Specific to RCTs, a quality and utility analysis based on the CONSORT guidelines and a usefulness checklist was adapted. An analysis by continents and proportion of RCTs published was also performed. Bibliometric network maps were created to determine trends in pre-eclampsia literature.
In total, 9654 articles were identified, with a doubling in the number of annual average publications from 310 to 655 between 1997 and 2016. This increase occurred in both English and non-English publications. There was a decline in the proportion of publications from selected high-impact journals from 22% in 1997-2001 to 8% in 2012-2016. Out of the available 130 RCTs that we analyzed, the number of RCTs published in 5-yearly periods remained relatively stable between 1987 and 2016, with quality and utility scores increasing from 24.6 and 11.6 to 31.9 and 13.3, respectively. A geographical search by continents showed that North America produced the majority of RCTs, followed by Asia and Europe. For completed pre-eclampsia trials that were registered between 2005 and 2014, only 68% resulted in peer-reviewed publications.
The yearly number of publications on pre-eclampsia has substantially increased, with a stable number of high-level study types and publications from high-impact journals. The reporting quality and usefulness of RCTs relating to pre-eclampsia have improved over time.
近年来，有关子痫前期的信息量不断增加。我们分析了 1997 年至 2016 年间子痫前期文献的趋势，并报告了 1987 年至 2016 年间随机对照试验（RCT）的质量和实用性。
我们在 PubMed 中搜索了标题中包含“子痫前期”或“妊娠高血压疾病”的所有文章，时间范围为 1997 年至 2016 年（一般文献）和 1987 年至 2016 年（RCT）。我们根据研究类型、语言以及来自高影响力期刊的出版物进行了分析。具体到 RCT，我们根据 CONSORT 指南和有用性清单进行了质量和实用性分析。我们还对各大洲和发表的 RCT 比例进行了分析。我们创建了文献计量网络图，以确定子痫前期文献的趋势。
共确定了 9654 篇文章，1997 年至 2016 年，每年平均出版物数量增加了一倍，从 310 篇增加到 655 篇。这种增加发生在英语和非英语出版物中。从选定的高影响力期刊中发表的论文比例从 1997-2001 年的 22%下降到 2012-2016 年的 8%。在我们分析的 130 项可用 RCT 中，1987 年至 2016 年间，每 5 年发表的 RCT 数量相对稳定，质量和实用性评分分别从 24.6 和 11.6 增加到 31.9 和 13.3。按大洲进行的地理搜索显示，北美发表的 RCT 最多，其次是亚洲和欧洲。对于在 2005 年至 2014 年期间注册的已完成子痫前期试验，只有 68%产生了同行评审出版物。
关于子痫前期的出版物数量逐年大幅增加，高水平研究类型和来自高影响力期刊的出版物数量保持稳定。关于子痫前期的 RCT 的报告质量和实用性随着时间的推移而提高。
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