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[copeptin——围手术期内稳态紊乱的一种新型生物标志物]

[Copeptin - a novel biomarker for perioperative homeostasis disorders].

作者信息

Mieszczański Piotr, Błaszczyk Beata, Śmietanowska-Więtczak Maryla, Trzebicki Janusz

机构信息

Warsaw Medical University, Poland: I Department of Anesthesiology and Intensive Care.

Warsaw Medical University, Poland: I Department of Anesthesiology and Intensive Care ∧ Chair and Department of Experimental and Clinical Physiology.

出版信息

Pol Merkur Lekarski. 2019 Sep 25;47(279):114-117.

Abstract

Recently there has been an increasing amount of research on copeptin as a novel biomarker for stress response and homeostasis disorders in a wide spectrum of morbidities. Copeptin is a stable and easily measured surrogate marker of arginine vasopressin and is increasingly included as a part of routine patient assessment tests in selected clinical scenarios. Such tests are also performed in the perioperative period, in which complication risk assessment is of exceptional importance. This review is an attempt to appraise up to date publications on use of copeptin as a biomarker.

摘要

最近,关于copeptin作为一种新型生物标志物在广泛疾病中应激反应和内稳态紊乱方面的研究越来越多。Copeptin是精氨酸加压素的一种稳定且易于测量的替代标志物,在特定临床情况下越来越多地被纳入常规患者评估测试的一部分。此类测试也在围手术期进行,其中并发症风险评估尤为重要。本综述旨在评估有关使用copeptin作为生物标志物的最新出版物。

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