呼吸机对肺不张患者的疗效：一项随机对照试验的系统评价方案
Efficacy of ventilator for patients with atelectasis: A systematic review protocol of randomized controlled trials.
作者信息
Wang Zhi-Guo, Sun Jian-Rong, Sha Hai-Wang
机构信息
Department of Elderly Respiratory Medicine, Cardiovascular and Cerebrovascular Specialist Ward Affiliated to Yanan University.
Department of Elderly Respiratory Medicine, Dongguan Hospital of Yanan University Affiliated Hospital.
出版信息
Medicine (Baltimore). 2019 Sep;98(39):e17259. doi: 10.1097/MD.0000000000017259.
BACKGROUND
This study aims to assess the efficacy and safety of ventilator for the treatment of atelectasis.
METHODS
We will search Cochrane Library, MEDLINE, EMBASE, CINAHL, EBSCO, Chinese database Chinese Biomedical Literature Database, China National Knowledge Infrastructure, and Wanfang data from inceptions to June 30, 2019 without language limitations. We will include randomized controlled trials (RCTs) of ventilator on evaluating the efficacy and safety of ventilator for atelectasis. We will use Cochrane risk of bias tool to assess the methodological quality for all included RCTs. RevMan 5.3 software will be used for statistical analysis.
RESULTS
The primary outcome is lung function. The secondary outcomes comprise of airway pressure, mean arterial pressure, arterial blood gas, heart rate, respiratory rate, oxygen saturation, and adverse events.
CONCLUSION
The findings of this study will provide most recent evidence of ventilator for the treatment of atelectasis.
SYSTEMATIC REVIEW REGISTRATION
PROSPERO CRD42019139329.
背景
本研究旨在评估通气治疗肺不张的有效性和安全性。
方法
我们将检索Cochrane图书馆、MEDLINE、EMBASE、CINAHL、EBSCO、中文数据库中国生物医学文献数据库、中国知网和万方数据，检索时间从建库至2019年6月30日，无语言限制。我们将纳入评估通气治疗肺不张有效性和安全性的随机对照试验（RCT）。我们将使用Cochrane偏倚风险工具评估所有纳入RCT的方法学质量。将使用RevMan 5.3软件进行统计分析。
结果
主要结局是肺功能。次要结局包括气道压力、平均动脉压、动脉血气、心率、呼吸频率、血氧饱和度和不良事件。
结论
本研究结果将为通气治疗肺不张提供最新证据。
系统评价注册
PROSPERO CRD42019139329。
Zotero 插件