Department of Abdominal Surgery, University Hospitals Leuven, Leuven, Belgium.
Interuniversity Center for Biostatistics and Statistical Bioinformatics, KU Leuven, University of Leuven and University of Hasselt, Leuven, Belgium.
Acta Chir Belg. 2021 Apr;121(2):86-93. doi: 10.1080/00015458.2019.1675969. Epub 2019 Oct 16.
To determine the incidence and to investigate risk factors for surgical site infections (SSIs) in a cohort of patients undergoing colorectal surgery.
MATERIAL & METHODS: Data from all consecutive patients operated at our department in an elective or in an urgent setting over a 4-month period were prospectively collected and analysed. The updated Centres for Disease Control and Prevention guidelines were used to define and to score SSIs during weekly meetings. Multivariate analysis was performed considering a list of 20 potential perioperative risk factors.
A total of 287 patients (mean age 56.9 ± 16.8 years, 51.2% male) were included. Thirty-five patients (12.2%) developed SSI. Independent risk factors for SSI were BMI <20 kg/m (OR 3.70; = .022), cancer (OR 0.33; = .046), respiratory comorbidity (OR 3.15; = .035), presence of a preoperative stoma (OR 3.74; = .003), and operative time ≥3 hours (OR 2.93; = .014).
Identified incidence and risk factors for the development of SSI after colorectal surgery were consistent with those already reported in the literature. The possibility to develop a validated prediction model for SSIs warrants further investigation, in order to target specific preventive measures on high-risk population.
确定接受结直肠手术患者的手术部位感染(SSI)发生率,并探讨其危险因素。
在 4 个月的时间内,前瞻性地收集并分析了在我院择期或紧急情况下进行手术的所有连续患者的数据。使用最新的疾病控制与预防中心指南,在每周的会议上定义和评分 SSI。考虑了 20 个潜在围手术期危险因素列表进行多变量分析。
共纳入 287 例患者(平均年龄 56.9±16.8 岁,51.2%为男性)。35 例患者(12.2%)发生 SSI。SSI 的独立危险因素为 BMI<20kg/m(OR 3.70;.022)、癌症(OR 0.33;.046)、呼吸系统合并症(OR 3.15;.035)、术前存在造口(OR 3.74;.003)和手术时间≥3 小时(OR 2.93;.014)。
确定结直肠手术后 SSI 发展的发生率和危险因素与文献报道的一致。进一步研究开发验证性 SSI 预测模型的可能性是值得的,以便针对高危人群采取特定的预防措施。