Division of Anesthesiology, Intensive Care, and Pain Medicine, Sackler Faculty of Medicine, Tel-Aviv Medical Center, Tel-Aviv University, Tel Aviv, Israel.
Department of Otolaryngology Head and Neck and Maxillofacial Surgery, Pediatric Otolaryngology Unit, Tel Aviv Medical Center, Dana-Dwek Children's Hospital, Tel Aviv Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Acta Anaesthesiol Scand. 2020 Mar;64(3):292-300. doi: 10.1111/aas.13488. Epub 2019 Oct 23.
Obstructive sleep apnea (OSA) occurs in 1%-4% of children; adenotonsillectomy is an effective treatment. Mortality/severe brain injury occurs among 0.6/10 000 adenotonsillectomies; in children, 60% are secondary to airway/respiratory events. Earlier studies identified that children aged <2 years, extremes of weight, with co-morbidities of craniofacial, neuromuscular, cardiac/respiratory disease, or severe OSA are at high risk for adverse post-operative respiratory events (AE). We aimed to: Firstly, investigate which risk factors were associated with AEs either in the post-anesthesia care unit (PACU), pediatric intensive care unit (PICU), or both in this population. Secondly, we investigated factors associated with post-operative PICU AE despite no event in the PACU in order to predict need of post-operative PICU after their PACU stay.
Retrospective study of children admitted to the PICU after adenotonsillectomy between 08/2006-09/2015. Demographics, risk factors, and occurrence of AE (oxygen saturation <92, stridor, bronchospasm, pneumonia, pulmonary edema, re-intubation) were recorded.
During the studied time period 4029 tonsil/adenoid procedures were performed in 3997 children. 179, admitted to the PICU post-operatively, met criteria for analysis. PICU AEs occurred in 59%: 44%-83% in any particular risk category. PACU AEs occurred in 42%. Of those with PACU events: 92% suffered AEs in the PICU; however, 35% of those without a PACU AE still suffered a PICU AE.
Among high-risk children undergoing TA, absence of adverse events in PACU during a 2-hour observation period does not predict absence of subsequent AEs in the PICU.
阻塞性睡眠呼吸暂停(OSA)在 1%-4%的儿童中发生;腺样体扁桃体切除术是一种有效的治疗方法。0.6/10000 例腺样体扁桃体切除术中会发生死亡/严重脑损伤;在儿童中,60%继发于气道/呼吸事件。早期研究表明,年龄<2 岁、体重极端、伴有颅面、神经肌肉、心脏/呼吸疾病或严重 OSA 的合并症的儿童,发生术后呼吸不良事件(AE)的风险较高。我们的目的是:首先,研究在该人群中,哪些危险因素与麻醉后监护病房(PACU)、儿科重症监护病房(PICU)或两者中的 AE 相关。其次,我们研究了尽管在 PACU 中没有发生事件,但与术后 PICU AE 相关的因素,以便预测其在 PACU 停留后的术后 PICU 需求。
对 2006 年 8 月至 2015 年 9 月间行腺样体扁桃体切除术并入住 PICU 的儿童进行回顾性研究。记录人口统计学、危险因素和 AE(血氧饱和度<92%、喘鸣、支气管痉挛、肺炎、肺水肿、重新插管)的发生情况。
在所研究的时间段内,3997 名儿童中有 4029 例扁桃体/腺样体手术。179 名术后入住 PICU 的儿童符合分析标准。PICU AE 发生率为 59%:在任何特定风险类别中为 44%-83%。PACU AE 发生率为 42%。在有 PACU 事件的儿童中:92%在 PICU 中发生 AE;然而,35%无 PACU AE 的儿童仍发生 PICU AE。
在接受 TA 的高危儿童中,在 2 小时观察期内 PACU 无不良事件并不能预测随后在 PICU 中是否发生 AE。