《胃肠病学家对代偿期肝硬化预防性管理指南》
The Gastroenterologist's Guide to Preventive Management of Compensated Cirrhosis.
作者信息
Shetty Akshay, Jun Yum Jung, Saab Sammy
机构信息
Dr Shetty is a fellow in the Department of Medicine, Mr Yum is a research assistant in the Department of Surgery, and Dr Saab is a professor in the Departments of Medicine and Surgery at the University of California, Los Angeles in Los Angeles, California.
出版信息
Gastroenterol Hepatol (N Y). 2019 Aug;15(8):423-430.
Despite advances in medical care, the prevalence and mortality associated with cirrhosis continue to rise. The majority of medical care and physician efforts are devoted to the management of decompensated cirrhosis and its complications of gastrointestinal hemorrhage, hepatic encephalopathy, and ascites; however, limited efforts are placed on the medical management of compensated cirrhosis. Patients with compensated cirrhosis carry a higher survival rate, and, when diagnosed early, may be screened for future decompensation. When possible, these patients can be treated for their underlying disease to prevent disease progression and avoid the need for liver transplantation. This article reviews the importance of early diagnosis, outpatient management of compensated cirrhosis, early screening for potential decompensation, and patient education.
尽管医疗护理取得了进展，但与肝硬化相关的患病率和死亡率仍在持续上升。大多数医疗护理和医生的工作都致力于失代偿期肝硬化及其胃肠道出血、肝性脑病和腹水等并发症的管理；然而，在代偿期肝硬化的医疗管理方面投入的精力有限。代偿期肝硬化患者的生存率较高，如果早期诊断，可对未来的失代偿情况进行筛查。在可能的情况下，这些患者可以针对其基础疾病进行治疗，以防止疾病进展并避免肝移植的需要。本文综述了早期诊断、代偿期肝硬化门诊管理、潜在失代偿的早期筛查以及患者教育的重要性。
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