可逆性黑舌：亚胺培南/西司他丁的一个鲜为人知的副作用及其作用机制的新证据。
Reversible black tongue: A little known side effect of imipenem/cilastatin and evidence for novel mode of action.
机构信息
Department of Pharmacy, People's Hospital of Henan Province, Zhengzhou, China.
Department of Orthopedics, People's Hospital of Henan Province, Zhengzhou, China.
出版信息
J Clin Pharm Ther. 2020 Apr;45(2):370-372. doi: 10.1111/jcpt.13066. Epub 2019 Oct 17.
WHAT IS KNOWN AND OBJECTIVE
Black tongue syndrome (BT) is a rare and self-limiting disorder which can result from physiological and metabolic condition and ingestion of toxic substances. Medications are the most common cause of BT.
CASE SUMMARY
A 39-year-old male patient presented with BT after the initiation of imipenem/cilastatin. Within one week of cessation of these drugs, the patient's tongue returned to a normal colour.
WHAT IS NEW AND CONCLUSION
This is the first case of BT induced by imipenem/cilastatin. Withdrawal of the combination is likely to reverse the condition.
已知和目的
黑舌综合征（BT）是一种罕见的自限性疾病，可能由生理和代谢状况以及有毒物质摄入引起。药物是 BT 最常见的原因。
病例总结
一名 39 岁男性患者在使用亚胺培南/西司他丁后出现 BT。停止使用这些药物一周内，患者的舌头恢复正常颜色。
新内容和结论
这是首例由亚胺培南/西司他丁引起的 BT 病例。停用该联合药物可能会逆转病情。
Zotero 插件