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前葡萄膜炎相关性霍奇金淋巴瘤致严重低眼压性黄斑病变。

Severe Hypotony Maculopathy in Anterior Uveitis Associated with Hodgkin Lymphoma.

机构信息

Department of Ophthalmology, IRCCS Ospedale San Raffaele, University Vita-Salute San Raffaele, Milan, Italy.

出版信息

Ocul Immunol Inflamm. 2021 Apr 3;29(3):460-464. doi: 10.1080/09273948.2019.1668952. Epub 2019 Oct 24.

Abstract

: To describe the clinical course and management of anterior uveitis complicated by ocular hypotony associated with Hodgkin lymphoma.: Case report.: Chart and multimodal imaging review, including ultrasound biomicroscopy, widefield fundus pictures, fundus autofluorescence, fluorescein angiography, and indocyanine green angiography.: A 44-year-old female with progressive visual deterioration and history of low-grade fever developed bilateral granulomatous anterior uveitis complicated by severe hypotony maculopathy, not improving with systemic and topical steroids. After starting ibopamine 2% eye drops, ocular hypotony progressively resolved with visual recovery. Histologic examination of a biopsied enlarged lymph node of the neck revealed the presence of Hodgkin lymphoma, for which the patient underwent systemic chemotherapy.: Severe hypotony maculopathy complicating anterior uveitis can be associated with Hodgkin lymphoma. Topical ipobamine 2% was safe and effective in the treatment of ocular hypotony in this case.

摘要

: 描述一例与霍奇金淋巴瘤相关的前葡萄膜炎合并眼球低眼压的临床经过和处理方法。: 病例报告。: 对图表和多种模式成像进行回顾,包括超声生物显微镜、广角眼底照片、眼底自发荧光、荧光素血管造影和吲哚青绿血管造影。: 一名 44 岁女性,因进行性视力下降和低热病史,出现双侧肉芽肿性前葡萄膜炎,合并严重的低眼压性黄斑病变,全身和局部应用皮质类固醇后未见改善。开始使用 2%异山梨醇滴眼液滴眼后,眼球低眼压逐渐缓解,视力恢复。对颈部肿大的淋巴结活检显示存在霍奇金淋巴瘤,患者接受了全身化疗。: 严重的低眼压性黄斑病变合并前葡萄膜炎可与霍奇金淋巴瘤相关。在本例中,局部使用 2%异山梨醇滴眼液治疗低眼压安全有效。

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