一例影像学表现为亚急性多灶性白质脑病的孤立性皮质静脉血栓形成病例及文献复习
A case of isolated cortical venous thrombosis presenting radiographically as a subacute multifocal leukoencephalopathy, and review of literature.
作者信息
Palmer Charles Francis, Khalighinejad Farnaz, Jun-O'Conell Adalia, Ionete Carolina
机构信息
Department of Neurology, Medical University of South Carolina, Charleston, South Carolina, USA.
Department of Neurology, University of Massachusetts Medical School, Worcester, Massachusetts, USA
出版信息
BMJ Case Rep. 2019 Oct 25;12(10):e230915. doi: 10.1136/bcr-2019-230915.
A 55-year-old man presented with brief seizure with associated acute aphasia, right head turn and subsequent generalised convulsion. On imaging, he was found to have patchy juxtacortical and cortical T2 hyperintensity with high radiographic suspicion for subacute multifocal leukoencephalopathy. Serum and cerebrospinal fluid testing were unremarkable. Clinically, the patient recovered completely and had no recurrence of symptoms. On follow-up MRI 1 month later, the T2 hyperintensity had resolved almost entirely while hypointensity on susceptibility-weighted angiography MRI remained, suggesting isolated cortical venous thrombosis.
一名55岁男性出现短暂性癫痫发作，伴有急性失语、头向右侧转动及随后的全身性惊厥。影像学检查发现，他存在斑片状皮质下及皮质T2高信号，高度怀疑为亚急性多灶性白质脑病。血清和脑脊液检查无异常。临床上，患者完全康复，症状未复发。1个月后的随访MRI显示，T2高信号几乎完全消失，而磁敏感加权血管造影MRI上的低信号仍然存在，提示孤立性皮质静脉血栓形成。
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