Cofano F, Berjano P, Vercelli G, Palmieri G, Pejrona M, Zenga F, Garbossa D
Department of Neurosurgery, Neuroscience - University of Turin, Via Cherasco 15, 10126, Turin, Italy.
IRCCS Istituto Ortopedico Galeazzi, Via R. Galeazzi 4, 20161, Milan, Italy.
Eur Spine J. 2020 Jul;29(7):1717-1723. doi: 10.1007/s00586-019-06192-x. Epub 2019 Oct 29.
Spontaneous regressions of calcified thoracic disc herniations (TDH) have been rarely described. Since now, no previous papers hypothesized that radiological factors could be able to predict the evolution of the herniation. This study shows that the radiodensity of the herniated material in herniations with spontaneous resolution might differ from that of operated herniations.
This is a retrospective study. A cohort of patients that underwent surgical removal of a calcified thoracic disc herniation has been compared to two cases conservatively treated and a case with spontaneous regression. CT scans were evaluated to compute the average radiodensity [in Hounsfield units (HU)] of the calcified components of the herniations. All the slices of the CT scans involving the calcification were evaluated in their axial images and in their coronal and sagittal reformations. Comparison of the slices radiodensity (spontaneously resolved versus surgically treated) was performed with the unpaired Student's t test.
The mean density of calcification in the case with spontaneous regression was found to be 454 HU. In the control group of surgical cases observed, and the conservatively treated cases, the mean HU density showed higher values (respectively, 827 and 853 HU) (p < 0.01).
Qualitative differences between calcified TDH that resolve spontaneously or need surgical treatment might be shown by differences of radiodensity. This comparative study, in spite of the limitations due to small numbers, provides a new insight in the interpretation of the phenomenon of spontaneous resolution of calcified TDH. These slides can be retrieved under Electronic Supplementary Material.
钙化性胸椎间盘突出症(TDH)的自发消退鲜有报道。迄今为止,尚无先前的论文假设放射学因素能够预测椎间盘突出症的发展。本研究表明,自发消退的椎间盘突出症中突出物质的放射密度可能与手术治疗的椎间盘突出症不同。
这是一项回顾性研究。将一组接受手术切除钙化性胸椎间盘突出症的患者与两例保守治疗的病例以及一例自发消退的病例进行了比较。对CT扫描进行评估,以计算椎间盘突出症钙化成分的平均放射密度[以亨氏单位(HU)表示]。对涉及钙化的CT扫描的所有切片在其轴向图像以及冠状面和矢状面重建图像中进行评估。采用不成对t检验对切片的放射密度(自发消退组与手术治疗组)进行比较。
发现自发消退病例的钙化平均密度为454 HU。在观察到的手术病例对照组和保守治疗病例中,平均HU密度显示出更高的值(分别为827和853 HU)(p < 0.01)。
自发消退或需要手术治疗的钙化性TDH之间的定性差异可能通过放射密度的差异来体现。尽管本比较研究因样本量小存在局限性,但为解释钙化性TDH的自发消退现象提供了新的见解。这些幻灯片可在电子补充材料中获取。