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基于临床发现建立产后生殖器血肿的治疗算法。

Establishing a Treatment Algorithm for Puerperal Genital Hematoma Based on the Clinical Findings.

机构信息

Department of Obstetrics and Gynecology, Fukushima Medical University School of Medicine.

Fukushima Medical Center for Children and Women, Fukushima Medical University School of Medicine.

出版信息

Tohoku J Exp Med. 2019 Oct;249(2):135-142. doi: 10.1620/tjem.249.135.

Abstract

Postpartum hemorrhage within 24 hours after delivery remains the leading cause of maternal mortality worldwide. Puerperal genital hematoma (PGHA) is a rare complication of postpartum hemorrhage, and PGHA can be life-threatening if hemostasis is not properly achieved. However, a reliable management algorithm for PGHA based on the clinical findings has not been developed. The objectives were to evaluate the management strategies for PGHA and identify the clinical findings that help select the treatment for PGHA. The medical records of women who were treated for PGHA in our department were reviewed, and data regarding the clinical findings and the treatment strategy for PGHA were analyzed. Thirty-four women who underwent treatment for PGHA were identified and divided into three groups according to the final procedure that achieved hemostasis: conservative management (CM) (n = 9), surgical management (SURG) (n = 15), and arterial embolization management (AEM) (n = 10). Regarding the clinical findings on initial evaluation, the shock index was significantly higher in the AEM group than in the CM or SURG group; and initial platelet count and fibrinogen level were significantly lower in the AEM group than in the CM group. There was no significant difference in any computed tomography (CT) finding among the three groups. In conclusion, this study clearly shows the difference in clinical findings among treatment strategies for PGHA. We suggest that the clinical findings of shock index, platelet count, and fibrinogen level together with CT findings are helpful and valuable for selecting the treatment strategy for PGHA.

摘要

产后 24 小时内出血仍然是全球产妇死亡的主要原因。产褥期生殖器血肿(PGHA)是产后出血的罕见并发症,如果不能正确止血,PGHA 可能危及生命。然而,尚未基于临床发现制定 PGHA 的可靠管理算法。目的是评估 PGHA 的治疗策略,并确定有助于选择 PGHA 治疗方法的临床发现。回顾了我院治疗 PGHA 的女性患者的病历,分析了 PGHA 的临床发现和治疗策略的数据。确定了 34 名接受 PGHA 治疗的女性患者,并根据最终实现止血的程序将其分为三组:保守治疗(CM)(n = 9)、手术治疗(SURG)(n = 15)和动脉栓塞治疗(AEM)(n = 10)。关于初始评估的临床发现,在 AEM 组中休克指数明显高于 CM 或 SURG 组;并且 AEM 组的初始血小板计数和纤维蛋白原水平明显低于 CM 组。三组之间的任何 CT 发现均无显着差异。总之,本研究清楚地显示了 PGHA 治疗策略之间临床发现的差异。我们建议休克指数、血小板计数和纤维蛋白原水平的临床发现以及 CT 发现有助于并对选择 PGHA 的治疗策略具有价值。

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