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应对遗传学领域的专利碎片化问题:专利池能否推动CRISPR基因编辑技术的发展?

Dealing with Patent Fragmentation in Genetics: Can Patent Pools Facilitate the Development of CRISPR Gene-Editing Technology?

作者信息

Stasi Alessandro, Rodrigues Isabel Pereira

机构信息

Senior Lecturer in Business Law and Biotechnology Law, Business Administration Division, Mahidol University International College.

Lecturer in Business Economics, Business Administration Division, Mahidol University International College Reseacher Fellow with Center for Advanced Studies in Management and Economics (CEFAGE), Universidade de Évora, Portugal.

出版信息

J Law Med. 2019 Jul;26(4):866-873.

Abstract

The discovery of CRISPR systems has been one of the most exciting developments in the field of genetics in the past decade. The recent proliferation of intellectual property rights for CRISPR genome editing technology carries the risk of potential bottlenecks for further basic biological research and development of commercial products. To make CRISPR-based technology widely available, the reliance by the industry on efficient methods of collective management of intellectual property rights through patent pools seems inevitable. A packager of patent pools could be used as a mechanism to facilitate transactions in the market for technology and allow interested parties to deal with a single entity. This article argues that, while a global licensing platform could be effectively achieved in non-therapeutic applications of genome editing, it is questionable whether patent pooling would provide the ideal balance of incentive and reward for CRISPR genome editing technologies for human gene therapy.

摘要

CRISPR系统的发现是过去十年遗传学领域最令人兴奋的进展之一。最近CRISPR基因组编辑技术知识产权的激增,给进一步的基础生物学研究和商业产品开发带来了潜在瓶颈的风险。为了使基于CRISPR的技术广泛可用,行业对通过专利池进行知识产权集体管理的有效方法的依赖似乎不可避免。专利池打包者可以作为一种机制,促进技术市场中的交易,并让相关方与单一实体打交道。本文认为,虽然在基因组编辑的非治疗应用中可以有效实现全球许可平台,但专利池是否能为人类基因治疗的CRISPR基因组编辑技术提供激励和回报的理想平衡,仍值得怀疑。

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