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可预防的移植后输尿管积水原因:移植输尿管腹股沟疝:病例报告及文献复习。

A preventable cause of transplant hydroureteronephrosis: inguinal herniation of the transplant ureter: case report and review of the literature.

机构信息

Department of Surgery, Universitair Ziekenhuis Brussel, Jette, Belgium.

Department of Urology, Universitair Ziekenhuis Brussel, Jette, Belgium.

出版信息

Acta Chir Belg. 2021 Oct;121(5):340-345. doi: 10.1080/00015458.2019.1689650. Epub 2019 Nov 14.

Abstract

BACKGROUND

Transplant ureter obstruction is an important cause of graft loss after kidney transplantation. Most cases occur early after transplantation and are related to surgical causes or ischaemic strictures. Underlying mechanisms of late ureteral obstruction are less well understood.

CASE REPORT

We present the case of a 61-year-old man who showed gradual decline in renal allograft function and hydronephrosis nine years after transplantation, due to an inguinal herniation of the transplant ureter. After urinary diversion using a percutaneous nephrostomy, graft function restored and the patient underwent surgery. The ureter was reduced from the inguinal hernia and re-implanted in the bladder, with primary closure of the abdominal wall defect. Postoperative course was uneventful and serum creatinine returned to baseline levels.

DISCUSSION

Search of relevant literature revealed a number of similar cases, which allowed identification of risk factors associated to the development of uretero-inguinal herniation leading to obstructive nephropathy. Diagnosis of this rare cause of transplant dysfunction and operative treatment strategies are discussed.

CONCLUSIONS

Inguinal herniation of the transplant ureter leading to ureteral obstruction is a rare, probably underreported, cause graft of dysfunction. Therefore, we advocate elective repair of inguinal or incisional hernias in renal transplant recipients.

摘要

背景

移植输尿管梗阻是肾移植后移植物丢失的一个重要原因。大多数病例发生在移植后早期,与手术原因或缺血性狭窄有关。输尿管晚期梗阻的潜在机制了解较少。

病例报告

我们报告了一例 61 岁男性的病例,该患者在移植后 9 年因移植输尿管腹股沟疝逐渐出现肾功能不全和肾积水。经皮肾造口术进行尿液引流后,移植物功能恢复,患者接受了手术。输尿管从腹股沟疝中复位,并重新植入膀胱,同时腹壁缺损行一期缝合。术后过程顺利,血清肌酐恢复至基线水平。

讨论

检索相关文献发现了一些类似的病例,这些病例确定了导致梗阻性肾病的输尿管-腹股沟疝发展的相关危险因素。讨论了这种罕见的移植物功能障碍原因的诊断和手术治疗策略。

结论

移植输尿管的腹股沟疝导致输尿管梗阻是一种罕见的、可能被低估的移植物功能障碍原因。因此,我们主张对肾移植受者的腹股沟疝或切口疝进行选择性修复。

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