Bautista-Hernandez Victor, Avila-Alvarez Alejandro, Marx Gerald R, Del Nido Pedro J
Servicio de Cirugía Cardiovascular, Complexo Hospitalario Universitario de A Coruña (CHUAC), A Coruña, España; Cardiopatía Estructural y Congénita, Instituto de Investigación Biomédica A Coruña (INIBIC), A Coruña, España.
Cardiopatía Estructural y Congénita, Instituto de Investigación Biomédica A Coruña (INIBIC), A Coruña, España; Unidad de Neonatología, Servicio de Pediatría, Complexo Hospitalario Universitario de A Coruña (CHUAC), A Coruña, España.
An Pediatr (Engl Ed). 2019 Nov;91(5):352.e1-352.e9. doi: 10.1016/j.anpedi.2019.09.007. Epub 2019 Nov 4.
Since the first successful palliation was performed by Norwood et al. in 1983, there have been substantial changes in diagnosis, management, and outcomes of hypoplastic left heart syndrome, Survival for stage 1 palliation has increased to 90% in many centres, with patients potentially surviving into adulthood. However, the associated morbidity and mortality remain substantial. Although the principles of staged surgical palliation of hypoplastic left heart syndrome are well established, there is significant variability in surgical procedure and management between centres, and several controversial aspects remain unresolved. In this review, we summarize the current surgical and management options for newborns with hypoplastic left heart syndrome and their outcomes.
自1983年诺伍德等人首次成功实施姑息治疗以来,左心发育不全综合征的诊断、治疗及预后已发生了重大变化。许多中心一期姑息治疗的生存率已升至90%,患者有可能存活至成年。然而,相关的发病率和死亡率仍然很高。尽管左心发育不全综合征分期手术姑息治疗的原则已确立,但各中心在手术操作和治疗方面仍存在显著差异,一些有争议的方面尚未得到解决。在本综述中,我们总结了目前针对左心发育不全综合征新生儿的手术和治疗选择及其预后。