Suppr超能文献

[精索去分化脂肪肉瘤一例]

[A Case of Dedifferentiated Liposarcoma of the Spermatic Cord].

作者信息

Tobiume Motoi, Aoki Shigeyuki, Yamada Yoshiaki, Hara Koji, Muramatsu Hiroyuki, Nishikawa Genya, Ono Kenzo, Nakamura Kogenta

机构信息

The Department of Urology, Japan Organization of Occupational Health and Safety Asahi Rosai Hospital.

The Department of Urology, Japan Community Health Care Organization Kani Tono Hospital.

出版信息

Hinyokika Kiyo. 2019 Oct;65(10):429-434. doi: 10.14989/ActaUrolJap_65_10_429.

Abstract

Liposarcomas are most commonly found in the extremities, in the retroperitoneum and, less often, in the head and neck area. The spermatic cord is a rare site of origin, accounting for about 4-7% of all liposarcomas. We report a case of dedifferentiated liposarcoma of the spermatic cord. A 51-year-old man was referred to our hospital for a painless hard mass in the left inguinal region. Abdominal computed tomography showed a left spermatic cord mass measuring 70 mm in diameter. We performed left high orchiectomy with resection of the mass. Immunohistochemical analysis revealed positive for murine double minute 2 (MDM 2) and cyclin dependent kinase 4 (CDK 4). Therefore, this sarcoma was diagnosed to be dedifferentiated liposarcoma. Since the surgical margin was positive, an additional wide resection including the surrounding normal tissue was performed. Complete excision was achieved after re-resection. He was alive 12 months postoperatively without any signs of recurrence. Dedifferentiated liposarcoma of the spermatic cord is a rare neoplasm. To the best of our knowledge, the present case is the 14th reported case in Japan.

摘要

脂肪肉瘤最常见于四肢、腹膜后,较少见于头颈部区域。精索是罕见的起源部位,约占所有脂肪肉瘤的4 - 7%。我们报告一例精索去分化脂肪肉瘤病例。一名51岁男性因左侧腹股沟区无痛性硬块被转诊至我院。腹部计算机断层扫描显示左侧精索肿块直径为70毫米。我们进行了左侧高位睾丸切除术并切除肿块。免疫组织化学分析显示鼠双微体2(MDM 2)和细胞周期蛋白依赖性激酶4(CDK 4)呈阳性。因此,该肉瘤被诊断为去分化脂肪肉瘤。由于手术切缘阳性,遂进行了包括周围正常组织的额外广泛切除。再次切除后实现了完整切除。术后12个月他仍存活,无任何复发迹象。精索去分化脂肪肉瘤是一种罕见肿瘤。据我们所知,本病例是日本第14例报告病例。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验