Department of Pediatrics, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Alberta, Canada.
School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
J Psychiatr Res. 2020 Jan;120:175-184. doi: 10.1016/j.jpsychires.2019.10.021. Epub 2019 Nov 1.
Mortality and morbidity rates related to prescription opioid analgesics have been rising in North America and may be a gateway to the nonmedical use of prescription opioids (NUPO). The purpose of this study was to explore correlates of NUPO in the adolescent population given the scarce literature in this area.
Cross-sectional data from 10,163 middle- and high-school students (15.1 ± 1.8 years old; 57.0% female; 55.6% White ethnic background) in Ontario were derived from the 2017 Ontario Student Drug Use and Health Survey. Potential correlates of NUPO in the past year included sociodemographic, behavioral, parental, and school characteristics.
Overall prevalence of NUPO was 10.7%. In the final multivariable model, NUPO was significantly associated with 8 of the 21 correlates examined. Students who used prescription opioids nonmedically were of black, South Asian, and "other" ethnic backgrounds (OR 2.83, OR 1.77, and OR 1.67, respectively); reported a lower subjective socioeconomic status (OR 0.92), lower parental support (OR 0.90), and lower academic performance (OR 0.86); met physical activity recommendations (OR 1.48); consumed energy drinks (OR 1.42); smoked tobacco cigarettes (OR 2.33); and used cannabis (OR 1.84).
Findings from this study show a wide variety of correlates of NUPO among Canadian adolescents, and highlight the need for further research and the value in targeted prevention and multi-level intervention programs for NUPO in this population.
在北美,与处方类阿片类镇痛药相关的死亡率和发病率一直在上升,这可能是导致非医疗用途处方类阿片类药物(NUPO)的一个途径。本研究的目的是探索青少年人群中与 NUPO 相关的因素,因为该领域的文献很少。
从安大略省 2017 年学生毒品使用和健康调查中获得了 10163 名中学生(15.1±1.8 岁;57.0%为女性;55.6%为白人种族背景)的横断面数据。过去一年中 NUPO 的潜在相关因素包括社会人口统计学、行为、父母和学校特征。
NUPO 的总体流行率为 10.7%。在最终的多变量模型中,NUPO 与 21 个相关因素中的 8 个显著相关。非医疗使用处方类阿片类药物的学生来自黑人、南亚裔和“其他”族裔背景(OR 分别为 2.83、1.77 和 1.67);报告较低的主观社会经济地位(OR 0.92)、较低的父母支持(OR 0.90)和较低的学业成绩(OR 0.86);符合体力活动建议(OR 1.48);消费能量饮料(OR 1.42);吸烟草香烟(OR 2.33);和使用大麻(OR 1.84)。
本研究的结果表明,加拿大青少年中存在广泛的与 NUPO 相关的因素,这突显了需要进一步研究,并需要为这一人群制定有针对性的预防和多层次干预计划,以预防和治疗 NUPO。