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西番莲果皮粉（西番莲）与姜黄粉（姜黄）对血糖控制的有效性：系统评价与荟萃分析

Effectiveness of Passion Fruit Peel Flour (Passiflora edulis L.) versus Turmeric Flour (Curcuma longa L.) on Glycemic Control: Systematic Review and Meta-Analysis.

作者信息

Sousa Danilo F, Veras Vivian S, Freire Vanessa E C S, Paula Maria L, Serra Maria A A O, Costa Ana C P J, da Conceição S O Cunha Maria, Queiroz Maria V O, Damasceno Marta M C, Paes Francisco E R, Freitas Roberto W J F, Araújo Márcio F M

机构信息

Nursing Department, Health Institute, University for International Integration of the Afro Brazilian Lusophony, Redencao, Brazil.

Nursing Department, Centre for Social Sciences, Health and Technology, Maranhao Federal University, Imperatriz, Brazil.

出版信息

Curr Diabetes Rev. 2020;16(5):450-456. doi: 10.2174/1573399815666191026125941.

DOI:10.2174/1573399815666191026125941

PMID:31738145

Abstract

BACKGROUND

It is undeniable that diabetes may cause several health complications for the population. Many of these complications are associated with poor glycemic control. Due to this, strategies to handle this problem are of great clinical importance and may contribute to reducing the various complications from diabetes.

OBJECTIVE

The aim of this study was to compare the effectiveness of the passion fruit peel flour versus turmeric flour on glycemic control.

METHODS

This is a systematic review and meta-analysis following the PRISMA protocol. The following inclusion criteria were applied: (1) Case-control studies, cohort studies, and clinical trials, due to the improved statistical analysis and, in restrict cases, cross-sectional studies; (2) Articles published in any language. The databases used for the search were PubMed, Scopus, Web of Science, Cochrane, and LILACS. A bias analysis and a meta-analyses were undertaken using R Studio (version 3.3.1) using effect- size models.

RESULTS

A total of 565 studies were identified from which 11 met the inclusion and exclusion criteria. Through isolated analysis, the effectiveness of turmeric flour on glycemic control was in the order of 0.73 CI (Confidence Interval) (from 0.68 to 0.79) and the effectiveness of passion fruit peel flour was 0.32 CI (0.23 to 0.45). The joint analysis resulted in 0.59 CI (0.52 to 0.68). The assessment of blood glucose was by glycated hemoglobin levels. All values were significant at a p < 0.05 level.

CONCLUSION

Both interventions showed significant effects on glycemic control.

摘要

背景

不可否认，糖尿病可能给人群带来多种健康并发症。其中许多并发症与血糖控制不佳有关。因此，应对这一问题的策略具有重要的临床意义，可能有助于减少糖尿病的各种并发症。

目的

本研究旨在比较西番莲果皮粉与姜黄粉对血糖控制的效果。

方法

这是一项遵循PRISMA协议的系统评价和荟萃分析。采用以下纳入标准：（1）病例对照研究、队列研究和临床试验，因其能改进统计分析，在受限情况下采用横断面研究；（2）以任何语言发表的文章。用于检索的数据库有PubMed、Scopus、科学网、Cochrane和LILACS。使用R Studio（版本3.3.1）采用效应量模型进行偏倚分析和荟萃分析。

结果

共识别出565项研究，其中11项符合纳入和排除标准。通过单独分析，姜黄粉对血糖控制的有效性为0.73置信区间（CI）（从0.68至0.79），西番莲果皮粉的有效性为0.32 CI（0.23至0.45）。联合分析得出的结果为0.59 CI（0.52至0.68）。血糖评估采用糖化血红蛋白水平。所有值在p < 0.05水平上均具有显著性。