经口CO₂激光显微手术治疗T1期声门癌后的肿瘤学结局
Oncological Outcomes Following Transoral CO Laser Microsurgery for T1 Glottic Cancer.
作者信息
Batra Ankur, Goyal A, Goyal M, Goel S
机构信息
Department of Otorhinolaryngology and Head & Neck Surgery, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, 110095 India.
出版信息
Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):542-547. doi: 10.1007/s12070-018-1394-4. Epub 2018 May 14.
The objective of this study is to analyze oncological outcomes for treatment of Tis and T1 glottic squamous cell carcinoma after transoral laser microsurgery. This study is retrospective analysis of previously untreated, suspected lesion of glottis, staged cT1a and cT1b squamous cell carcinoma in a tertiary care hospital and 53 patients were included in the study. End points for analysis were local control, overall and disease specific survival rates. The local control, ultimate local control with laser alone, 3-year overall survival, 3-year disease specific survival and organ preservation rates were 86.7, 90.5, 92.4, 98.1 and 98.1% respectively. The involvement of anterior commissure did not show any significant impact on local control or survival. TLM is safe and effective treatment of early glottis cancer, associated with less morbidity and a high percentage of local control, survival and organ preservation rates.
本研究的目的是分析经口激光显微手术治疗Tis和T1期声门鳞状细胞癌的肿瘤学结局。本研究是对一家三级护理医院中先前未经治疗的疑似声门病变、分期为cT1a和cT1b的鳞状细胞癌进行的回顾性分析，共有53例患者纳入研究。分析的终点为局部控制、总生存率和疾病特异性生存率。局部控制率、单纯激光治疗的最终局部控制率、3年总生存率、3年疾病特异性生存率和器官保留率分别为86.7%、90.5%、92.4%、98.1%和98.1%。前联合受累对局部控制或生存率未显示出任何显著影响。经口激光显微手术是早期声门癌的一种安全有效的治疗方法，具有较低的发病率以及较高的局部控制率、生存率和器官保留率。
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