Department of Chemistry and Chemical Engineering, Hunan Institute of Science and Technology, Yueyang 414006, China.
Org Biomol Chem. 2019 Dec 4;17(47):10020-10029. doi: 10.1039/c9ob02102g.
A simple and efficient visible-light-catalyzed cascade sulfonylation/cyclization of N-propargylindoles with K2S2O5 and aryldiazonium tetrafluoroborates for the construction of 2-sulfonyl-substituted 9H-pyrrolo[1,2-a]indoles is developed. In this transformation, K2S2O5 as a simple and inexpensive sulfur dioxide source provides sulfur dioxide for accessing sulfonyl radicals. This method features excellent functional group tolerance and offers a convenient route for assembling a new C-C bond and two new C-S bonds in one step.
发展了一种简单高效的可见光催化 N-炔丙基吲哚与 K2S2O5 和芳基重氮四氟硼酸盐的串联磺酰化/环化反应，用于构建 2-磺酰基取代的 9H-吡咯并[1,2-a]吲哚。在这个转化中，K2S2O5 作为一种简单且廉价的二氧化硫源，为磺酰基自由基的生成提供了二氧化硫。该方法具有优异的官能团容忍性，为在一步中构建新的 C-C 键和两个新的 C-S 键提供了一条便利途径。
