Division of General and Thoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Division of Interventional Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Pediatr Blood Cancer. 2020 Mar;67(3):e28029. doi: 10.1002/pbc.28029. Epub 2019 Nov 20.
Sclerotherapy or surgical resection is options for symptomatic venous malformations (VM). Sclerotherapy may require repetitive intervention and resection is often avoided due to operative morbidity. The purpose of this study was to report use of single-stage n-butyl cyanoacrylate glue embolization and surgical resection of focal VM.
A review of patients with focal VM who underwent glue embolization followed by resection at a single tertiary care vascular malformations center was performed. All embolizations were performed with ultrasound and fluoroscopy under the same anesthetic as resection. Patient characteristics and outcomes were evaluated.
Fifteen procedures were performed in 12 patients with a total of 20 VM addressed, as several patients had multiple VM. Mean age was 16 ± 9 years. Malformation locations included scalp, hip, gluteal, labial, toe, finger, face, lip, chest, and foot and size ranged from 1.0 to 10.5 cm. Median (range) of prior sclerotherapy treatments was 3 (0-5) and three patients previously underwent surgical resection. Median blood loss was zero (0-10) mL. Surgical complications occurred after five procedures (33%) including superficial wound dehiscence and cellulitis. No complications required readmission or reoperation. At a median follow up of 195 (103-266) days, no patients have required additional treatment.
Glue embolization and resection of focal VM of variable size and location appears to have durable results and low surgical morbidity. This single-stage procedure, often performed as an outpatient, may be utilized as upfront treatment for symptomatic malformations or for VM refractory to other treatments.
硬化疗法或手术切除是治疗症状性静脉畸形(VM)的选择。硬化疗法可能需要重复干预,并且由于手术发病率高,通常避免切除。本研究的目的是报告使用单次 n-丁基氰基丙烯酸酯胶栓塞和手术切除局灶性 VM。
对在单一三级血管畸形中心接受胶栓塞后再行切除术的局灶性 VM 患者进行回顾性研究。所有栓塞均在超声和透视引导下,与切除术在同一麻醉下进行。评估患者的特征和结局。
12 例患者共进行了 15 次手术,共治疗了 20 个 VM,因为一些患者有多个 VM。平均年龄为 16±9 岁。畸形部位包括头皮、臀部、臀肌、唇、脚趾、手指、面部、嘴唇、胸部、足部,大小从 1.0 至 10.5cm。中位数(范围)硬化治疗次数为 3(0-5),有 3 例患者曾接受过手术切除。中位出血量为 0(0-10)mL。5 例(33%)手术后出现手术并发症,包括浅表伤口裂开和蜂窝织炎。无并发症需要再次入院或再次手术。中位随访 195(103-266)天,无患者需要额外治疗。
大小和位置不同的局灶性 VM 的胶栓塞和切除术似乎具有持久的效果和低手术发病率。这种单一阶段的手术,通常作为门诊手术进行,可作为症状性畸形的初始治疗方法,或作为对其他治疗方法有抵抗的 VM 的治疗方法。