由四例罕见病例说明的异位促肾上腺皮质激素分泌检查中的潜在陷阱。
Possible pitfalls in the workup of ectopic ACTH secretion illustrated by four rare cases.
作者信息
Boers Jorianne, Oldenburg-Ligtenberg P Christine, Stades Aline Me, van Treijen Mark Jc
机构信息
Department of Internal Medicine, Meander Medical Centre, Amersfoort, Utrecht, The Netherlands.
Department of Endocrinology, University Medical Center Utrecht, Utrecht, The Netherlands.
出版信息
BMJ Case Rep. 2019 Nov 21;12(11):e231067. doi: 10.1136/bcr-2019-231067.
In this case report, we highlight four different cases of ectopic adrenocorticotropic hormone (ACTH) secretion with different pitfalls in the diagnostic workup. Ectopic ACTH secretion (EAS) is an uncommon cause of Cushing's syndrome that accompanies a variety of tumours. It is associated with significant morbidity and mortality. This underlines the importance of early and adequate diagnosis. We will review the causes of EAS and their presentation to increase awareness of this rare and progressive disease.
在本病例报告中，我们重点介绍了4例异位促肾上腺皮质激素（ACTH）分泌的不同病例，这些病例在诊断检查中存在不同的陷阱。异位ACTH分泌（EAS）是库欣综合征的一种罕见病因，可伴有多种肿瘤。它与显著的发病率和死亡率相关。这突出了早期和充分诊断的重要性。我们将回顾EAS的病因及其表现，以提高对这种罕见且进展性疾病的认识。
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