VCA West Los Angeles, Los Angeles, California.
J Vet Intern Med. 2020 Jan;34(1):283-288. doi: 10.1111/jvim.15666. Epub 2019 Nov 26.
A 6-month-old intact female Maltese dog was presented for acute onset of syncope.
The dog was presented for collapse upon excitement and exercise. It collapsed at discharge and suffered cardiopulmonary arrest. Echocardiography after resuscitation indicated severe pulmonary hypertension without evidence of intracardiac or extracardiac shunting. A presumptive diagnosis of congenital pulmonary hypertension was made.
Initial treatment with sildenafil was effective at relieving syncope, but the extent of pulmonary hypertension as determined by serial echocardiography was unchanged. Graded balloon atrial septostomy was performed as a palliative procedure. Follow-up echocardiography identified a patent interatrial communication with bidirectional shunting. The dog remained asymptomatic 18 months after treatment.
To the best of our knowledge, this study is the first report in the veterinary literature of graded balloon atrial septostomy performed for therapeutic purposes. Further studies are required to determine if this palliative procedure is a beneficial treatment option for dogs with congenital or severe refractory pulmonary hypertension.
一只 6 月龄未去势雌性马尔济斯犬因突发晕厥就诊。
该犬兴奋或运动时易出现晕厥和倒地,出院时倒地后出现心肺骤停。复苏后的超声心动图检查提示严重肺动脉高压,但无心脏内或心脏外分流的证据。疑似先天性肺动脉高压。
初始使用西地那非治疗晕厥有效,但多次超声心动图检查显示肺动脉高压程度无变化。进行分级球囊房间隔造口术作为姑息性治疗。后续超声心动图显示房间隔交通呈双向分流且开放。治疗后 18 个月,该犬无症状。
据我们所知,本研究是兽医文献中首次报道为治疗目的进行分级球囊房间隔造口术。需要进一步研究以确定该姑息性治疗方案是否对先天性或严重难治性肺动脉高压的犬有益。