Wielgosz A T, Wielgosz M, Biro E, Nicholls E, MacWilliam L, Haney T
Ottawa General Hospital, Ontario, Canada.
Br J Med Psychol. 1988 Sep;61(3):209-17. doi: 10.1111/j.2044-8341.1988.tb02782.x.
Several risk factors for acute myocardial infarction (AMI) were examined, including history of smoking and hypercholesterolemia, income, education, coronary-prone behaviour by Structured Interview (SI) and the type and quality of stress-reducing relaxing activities, in a case-control study. Our sample included 100 AMI patients (80 males and 20 females, with mean ages 57.3 and 64.1 years, respectively), as well as 100 age- and sex-matched controls. Univariate differences between cases and controls were significant for history of smoking, income level, SI-defined hostility, SI-defined suppression of hostility, amount and type of relaxing activities and history of hypercholesterolemia. Multivariable analyses demonstrated that AMI patients reported significantly lower levels of relaxation and income, but higher levels of suppressed hostility and a higher incidence of hypercholesterolemia. Our findings confirm the significance of hostility and particularly suppressed hostility as AMI risk factors; furthermore, inadequate relaxation was identified as an independent risk factor associated with AMI.
在一项病例对照研究中,对急性心肌梗死(AMI)的几个风险因素进行了检查,包括吸烟史、高胆固醇血症、收入、教育程度、通过结构化访谈(SI)评估的冠心病倾向行为以及减压放松活动的类型和质量。我们的样本包括100例AMI患者(80名男性和20名女性,平均年龄分别为57.3岁和64.1岁),以及100名年龄和性别匹配的对照。病例组和对照组在吸烟史、收入水平、SI定义的敌意、SI定义的敌意抑制、放松活动的数量和类型以及高胆固醇血症病史方面的单变量差异具有统计学意义。多变量分析表明,AMI患者报告的放松程度和收入水平显著较低,但敌意抑制水平较高,高胆固醇血症的发生率也较高。我们的研究结果证实了敌意尤其是敌意抑制作为AMI风险因素的重要性;此外,放松不足被确定为与AMI相关的独立风险因素。