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持续性牙-牙槽疼痛障碍:一种潜在的口腔内慢性重叠性疼痛状况。

Persistent dentoalveolar pain disorder: A putative intraoral chronic overlapping pain condition.

机构信息

Research Center, Hôpital du Sacré-Coeur de Montréal, CIUSSS du Nord-de-l'Île-de-Montréal, Faculty of Dental Medicine, Université De Montréal, Montreal, Canada.

Division of Experimental Medicine, McGill University, Montreal, Canada.

出版信息

Oral Dis. 2020 Nov;26(8):1601-1609. doi: 10.1111/odi.13248. Epub 2019 Dec 17.

Abstract

Chronic overlapping pain conditions (COPCs) are conditions that share several clinical characteristics and symptomatology, are usually considered idiopathic in nature, and are frequently comorbid. Currently, there are no established inclusion criteria to determine which conditions should be included under this umbrella term despite different systems proposed. Persistent dentoalveolar pain disorder (PDAP), also referred to as atypical odontalgia and thought to be a component of persistent idiopathic facial pain, is a chronic pain condition that manifests as a persistent tooth pain or pain over a dentoalveolar site formerly occupied by a tooth in the absence of detectable pathology during clinical or radiological examination. PDAP is considered idiopathic in nature, and its pathophysiological mechanisms are not fully understood. Our objective was to investigate whether PDAP fits the conceptual paradigm of COPC given its characteristics and commonalities with other COPC, based on published literature identified through a scoping review. We found that PDAP fits 16 out of 18 common characteristics among COPCs, and based on this finding, we discuss the implications of PDAP being considered a COPC.

摘要

慢性重叠性疼痛疾病(COPCs)是指具有若干临床特征和症状、通常被认为是特发性的、且常伴发的疾病。目前,尽管提出了不同的系统,但尚无确定哪些疾病应归入这一总括术语的既定纳入标准。持续性牙源性疼痛障碍(PDAP),也称为非典型牙痛,被认为是持续性特发性面部疼痛的一个组成部分,是一种以持续性牙痛或牙齿部位疼痛为表现的慢性疼痛疾病,在临床或影像学检查中无可检测到的病理学。PDAP 被认为是特发性的,其病理生理机制尚未完全阐明。我们的目的是通过系统评价确定的文献综述,根据其特征及其与其他 COPC 的共性,研究 PDAP 是否符合 COPC 的概念范式。我们发现,PDAP 符合 COPCs 中的 18 个共同特征中的 16 个,基于这一发现,我们讨论了将 PDAP 视为 COPC 的影响。

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