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经钕:钇-铝-石榴石激光腔内光凝治疗头颈部淋巴管畸形的长期随访。

Long Term Follow-up of Intralesional Laser Photocoagulation for Head and Neck Lymphatic Malformations Using Neodymium-Yttrium-Aluminium-Garnet Laser.

机构信息

Department of Plastic Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan City, Taiwan.

出版信息

Ann Plast Surg. 2020 Mar;84(3):288-292. doi: 10.1097/SAP.0000000000002049.

Abstract

BACKGROUND

Lymphatic malformations remain a challenge for patients and plastic surgeons. Promising results have been reported using intralesional laser photocoagulation (ILP) for treating vascular anomalies.

BACKGROUND DATA

The objective of our study is to review the long-term results of a large series of lymphatic malformations in patients treated with ILP.

MATERIALS AND METHODS

A retrospective review of 190 head and neck lymphatic malformations in patients were treated by ILP with an neodymium-yttrium-aluminum-garnet (Nd:YAG) laser (1064 nm) over a period of 20 years (January 1997-January 2016). Patients' ages ranged from 10 months to 12 years and 6 months (mean, 1 year and 11 months). The patient group consisted of 98 female and 92 male patients.

RESULTS

Patients were treated with an Nd:YAG laser (Sharplan Inc, Allendale, New Jersey) delivered through a 600-μm optical fiber. Laser power was set at 7 to 15 W and delivered with a pulse duration of 7 to 15 seconds. All patients demonstrated improvement as judged by clinical assessment of the reduction in lesion size (range, 65%-100%; mean reduction, 85%). One hundred fifty-two (80%) patients had a more than 65% reduction of the volume in lymphatic malformations at 3 months after 1 treatment, and 171 (90%) patients had a more than 85% reduction of the volume after 2 treatments. Excellent results were seen in 19 (10%) patients after 3 treatments. Postoperative complications were related to photocoagulation that was delivered too extensively or superficially, with resultant ulceration, infection, induration, and scarring.

CONCLUSIONS

Throughout the course of our long-term study, ILP using an Nd:YAG laser is an effective treatment modality for lymphatic malformations. Complications can be avoided if the potential for harm is kept in mind.

摘要

背景

淋巴管畸形仍然是患者和整形外科医生面临的挑战。使用腔内激光光凝(ILP)治疗血管畸形已取得可喜的效果。

背景资料

我们研究的目的是回顾用 ILP 治疗的大量淋巴管畸形患者的长期结果。

材料和方法

对 190 例头颈部淋巴管畸形患者进行回顾性分析,这些患者在 20 年期间(1997 年 1 月至 2016 年 1 月)接受了腔内激光光凝治疗,使用钕钇铝石榴石(Nd:YAG)激光(1064nm)。患者年龄为 10 个月至 12 岁零 6 个月(平均 1 岁 11 个月)。患者组包括 98 名女性和 92 名男性。

结果

患者接受 Nd:YAG 激光(Sharplan Inc,新泽西州艾伦代尔)治疗,通过 600μm 光纤传输。激光功率设置为 7 至 15W,脉冲持续时间为 7 至 15 秒。所有患者均根据病变大小减少的临床评估(范围为 65%-100%;平均减少 85%)判断有所改善。在 1 次治疗后 3 个月,152 例(80%)患者淋巴管畸形体积减少超过 65%,171 例(90%)患者体积减少超过 85%。在 3 次治疗后,19 例(10%)患者获得了极好的效果。术后并发症与光凝过度或过浅有关,导致溃疡、感染、硬结和瘢痕形成。

结论

在我们的长期研究过程中,Nd:YAG 激光腔内激光光凝是治疗淋巴管畸形的有效方法。如果能牢记潜在的危害,就能避免并发症。

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