Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Foundation Trust, WC1N 3JH, London, UK.
Pediatr Nephrol. 2021 Feb;36(2):287-294. doi: 10.1007/s00467-019-04424-2. Epub 2019 Dec 13.
Some children with declining height and BMI SDS fail to respond to optimisation of nutritional intake. As well as poor growth, they have muscle wasting and relative preservation of body fat. This is termed protein energy wasting (PEW). The process results from an interaction of chronic inflammation alongside poor nutritional intake. This review discusses the causes and potential preventative therapies for PEW.
一些身高和 BMI SDS 下降的儿童未能对营养摄入的优化做出反应。除了生长不良外,他们还存在肌肉消耗和体脂相对保留。这被称为蛋白质能量消耗(PEW)。该过程是由慢性炎症与不良营养摄入相互作用引起的。本文综述了 PEW 的病因和潜在预防治疗方法。