Department of Cardiothoracic Surgery, St George's Hospital, London, United Kingdom.
Department of Cardiology, St George's Hospital, London, United Kingdom.
Ann Thorac Surg. 2020 Sep;110(3):943-947. doi: 10.1016/j.athoracsur.2019.10.052. Epub 2019 Dec 14.
The 2 main techniques of valve-sparing aortic root replacement (VSRR) are remodeling and reimplantation. There is concern that the aortic annulus, which is not stabilized in remodeling technique, may dilate over time and cause aortic regurgitation. Our aim was to assess whether the aortic annulus dilates after VSRR with remodeling technique without aortic annuloplasty.
Data on patients undergoing elective or urgent VSRR remodeling technique between 2005 and 2018 were collected. Patients undergoing arch and emergency surgery for acute type A aortic dissection were excluded. Preoperative aortic annulus diameter was measured by transthoracic echocardiography, and this was compared with the annulus diameter measured from the most recently available transthoracic echocardiography. The requirement for reintervention during follow-up was recorded.
Between 2005 and 2018, 98 patients underwent VSRR. Sixty-six (67.3%) had Marfan syndrome or Loeys-Dietz syndrome. Median age was 60 (interquartile range, 18-68) years and 71 (72.4%) were men. Median cross-clamp and cardiopulmonary bypass times were 122 (interquartile range, 104-164) minutes and 138 (interquartile range, 121-198) minutes, respectively. Median intensive care unit and hospital stay were 1 day and 6 days, respectively. No patients suffered perioperative stroke. There was no in-hospital mortality. At median follow-up of 7.1 years (interquartile range, 5-129 months), mean postoperative annular diameter was 25.7 mm, from 24.2 mm preoperatively (P = .403). One patient required aortic valve replacement during follow-up. Freedom from moderate or severe aortic regurgitation was 97%.
There was no significant aortic annular dilatation in selected patients undergoing remodeling VSRR. Our data do not support routine use of annuloplasty in patients with annular diameter less than or equal to 25 mm.
保留瓣膜的主动脉根部替换术(VSRR)有两种主要技术,即重塑和再植入。人们担心在重塑技术中,主动脉瓣环未得到稳定,可能会随着时间的推移而扩张,并导致主动脉瓣反流。我们的目的是评估在不进行主动脉瓣环成形术的情况下,采用重塑技术进行 VSRR 后主动脉瓣环是否会扩张。
收集了 2005 年至 2018 年间接受择期或紧急 VSRR 重塑技术的患者的数据。排除了接受升主动脉弓和急诊手术治疗急性 A 型主动脉夹层的患者。术前通过经胸超声心动图测量主动脉瓣环直径,并将其与最近一次经胸超声心动图测量的瓣环直径进行比较。记录随访期间需要再次干预的情况。
2005 年至 2018 年间,98 例患者接受了 VSRR。66 例(67.3%)患有马凡综合征或 Loeys-Dietz 综合征。中位年龄为 60 岁(四分位间距,18-68 岁),71 例(72.4%)为男性。中位体外循环和心肺转流时间分别为 122 分钟(四分位间距,104-164 分钟)和 138 分钟(四分位间距,121-198 分钟)。中位重症监护病房和住院时间分别为 1 天和 6 天。无患者发生围手术期卒中。无院内死亡。中位随访 7.1 年(四分位间距,5-129 个月)时,术后平均瓣环直径为 25.7 毫米,术前为 24.2 毫米(P=.403)。1 例患者在随访期间需要进行主动脉瓣置换。无中度或重度主动脉瓣反流的生存率为 97%。
在接受重塑 VSRR 的选定患者中,主动脉瓣环无明显扩张。我们的数据不支持在瓣环直径小于或等于 25 毫米的患者中常规使用瓣环成形术。