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补充益生菌与接受胃肠道手术的新生儿住院时间的关系

Probiotics supplementation and length of hospital stay in neonates with gastrointestinal surgery.

作者信息

Mugarab-Samedi Veronica, Howlett Alixe, Hicks Mattew, Arrieta Marie-Claire, Beaudry Paul, Dersch-Mills Deonne, Alshaikh Belal

机构信息

Department of pediatrics, University of Calgary, Calgary, Canada.

Department of pediatrics, University of Alberta, Edmonton, Canada.

出版信息

Int J Surg Protoc. 2017 Oct 18;6:13-16. doi: 10.1016/j.isjp.2017.10.001. eCollection 2017.

Abstract

Any manipulation on open bowel causes interventional impact on gut microbiome, and surgical stress triggers bacterial translocation; thus, it will be fundamental to determine gut microbiome after surgery. Monitoring dynamic changes in microbiome of post-surgical infants who received probiotics and placebo could provide with important information about gut colonization and potential bacterial overgrowth. The purpose of this study is to assess the effect of probiotics supplementation on length of hospital stay, duration of parenteral nutrition, and feed tolerance in neonates after gastrointestinal surgery.

摘要

对开放肠道的任何操作都会对肠道微生物群产生干预性影响,手术应激会引发细菌移位;因此,确定术后的肠道微生物群至关重要。监测接受益生菌和安慰剂的术后婴儿微生物群的动态变化,可以提供有关肠道定植和潜在细菌过度生长的重要信息。本研究的目的是评估补充益生菌对新生儿胃肠道手术后住院时间、肠外营养持续时间和喂养耐受性的影响。

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本文引用的文献

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Probiotics for the postoperative management of term neonates after gastrointestinal surgery.
Cochrane Database Syst Rev. 2024 Jan 23;1(1):CD012265. doi: 10.1002/14651858.CD012265.pub2.
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