Mugarab-Samedi Veronica, Howlett Alixe, Hicks Mattew, Arrieta Marie-Claire, Beaudry Paul, Dersch-Mills Deonne, Alshaikh Belal
Department of pediatrics, University of Calgary, Calgary, Canada.
Department of pediatrics, University of Alberta, Edmonton, Canada.
Int J Surg Protoc. 2017 Oct 18;6:13-16. doi: 10.1016/j.isjp.2017.10.001. eCollection 2017.
Any manipulation on open bowel causes interventional impact on gut microbiome, and surgical stress triggers bacterial translocation; thus, it will be fundamental to determine gut microbiome after surgery. Monitoring dynamic changes in microbiome of post-surgical infants who received probiotics and placebo could provide with important information about gut colonization and potential bacterial overgrowth. The purpose of this study is to assess the effect of probiotics supplementation on length of hospital stay, duration of parenteral nutrition, and feed tolerance in neonates after gastrointestinal surgery.
对开放肠道的任何操作都会对肠道微生物群产生干预性影响,手术应激会引发细菌移位;因此,确定术后的肠道微生物群至关重要。监测接受益生菌和安慰剂的术后婴儿微生物群的动态变化,可以提供有关肠道定植和潜在细菌过度生长的重要信息。本研究的目的是评估补充益生菌对新生儿胃肠道手术后住院时间、肠外营养持续时间和喂养耐受性的影响。