Clinical Research Development Unit, Sina Educational, Research and Treatment Center, Department of Internal Medicine, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Clinical Toxicology Department, Urmia University of Medical Sciences, Urmia, Iran.
Basic Clin Pharmacol Toxicol. 2020 Jun;126(6):475-483. doi: 10.1111/bcpt.13380. Epub 2020 Jan 13.
Clinical toxicology is not recognized as a clinical speciality in Iran. After the chemical war gas attack by the Iraqi army against the Iranian troops in the 1980s, health professionals and Iranian authorities noticed the importance of this field in clinical medicine. Collaboration between the clinical toxicologists and toxicologists of pharmacy schools resulted in the establishment of the Iranian Society of Toxicology and Poisonings in 1991 and the National Board of Toxicology in 1993. Clinical toxicology fellowship was also formed as a joint collaboration between the toxicology and internal medicine boards in 2010. Medical doctors who specialized in clinical medicine are eligible to take the entrance examination of the fellowship. In spite of the advancement of clinical toxicology and increased number of acute poisonings and drug abuse, undergraduate teaching in this field is still lacking and being taught as part of the forensic medicine curriculum since 1952. There is a lack of an efficient national poison information and control centre (s) in Iran, and no action plan and practical efforts have been done for poisoning prevention. Therefore, the number of drug abuse and acute poisonings has increased over the past four decades and induced cultural, social and health problems. According to Iranian legal medicine organization reports, poisoning is the second-most occurring cause of unnatural death. The suicidal attempt is the most common method of acute poisoning in adults. Suicidal attempt including self-poisoning is not accepted in the Islamic point of view, and thus self-poisoning is mostly neglected and may not be treated appropriately in time in some regions of Iran. Accidental poisoning in children is also common in Iran and estimated to be between 20 000 and 25 000 cases annually over the recent years. In addition, social, cultural and economic problems have induced more health problems such as drug abuse and addiction even in children. Adulterated opium to lead for economic gaining has produced thousands of cases of lead poisoning over the past few years in nearly all opium addicts, which is still a major health problem in Iran. Ban on alcoholic beverages leads some people to make their own home-made spirits, which is unfortunately contaminated with methanol. Thousands of cases of methanol poisoning and even some epidemics have occurred over the past four decades in some parts of the country. Lack of availability of essential antidotes such as succimer and fomepizole has been a major problem for the effective treatment of poisoned patients. Despite the well-known fact that cases of poisoning and drug overdose constitute a significant proportion of hospital admissions in some developing countries, clinical toxicology education and medical care of the poisoned patients are lacking. Therefore, policymakers and health authorities should realize the importance of toxicology in clinical medicine. The Iranian Ministry of Health, medical care and Medical Education should implement clinical toxicology courses for medical students; establish effective national poisons information and control centres and advance clinical toxicology services for appropriate management of poisoned patients to improve public health and the overall health policy goals.
临床毒理学在伊朗尚未被视为一门临床专科。20 世纪 80 年代,伊拉克军队对伊朗军队发动化学战毒气袭击后,卫生专业人员和伊朗当局注意到了这一领域在临床医学中的重要性。临床毒理学家和药学院毒理学家之间的合作促成了 1991 年伊朗毒理学和中毒学会的成立和 1993 年国家毒理学委员会的成立。2010 年,毒理学和内科委员会还联合成立了临床毒理学研究员。专门从事临床医学的医生有资格参加研究员的入学考试。尽管临床毒理学取得了进展,急性中毒和药物滥用的数量有所增加,但自 1952 年以来,该领域的本科教学仍缺乏,并作为法医学课程的一部分进行教学。伊朗缺乏有效的国家毒物信息和控制中心(s),也没有制定预防中毒的行动计划和采取实际措施。因此,在过去四十年中,药物滥用和急性中毒的数量有所增加,引发了文化、社会和健康问题。根据伊朗法医学组织的报告,中毒是导致非自然死亡的第二大原因。成年人中最常见的急性中毒自杀企图。在伊斯兰教观点中,自杀性自我中毒是不可接受的,因此在伊朗的一些地区,自我中毒往往被忽视,可能无法及时得到适当治疗。儿童意外中毒在伊朗也很常见,近年来每年估计有 20000 至 25000 例。此外,社会、文化和经济问题导致了更多的健康问题,如药物滥用和成瘾,甚至在儿童中也是如此。为了经济利益而掺杂铅的鸦片在过去几年里导致了数千例铅中毒,这在伊朗仍然是一个主要的健康问题。禁止含酒精饮料导致一些人自制自制烈酒,不幸的是,这些烈酒受到甲醇污染。在过去的四十年里,该国的一些地区发生了数千例甲醇中毒甚至一些流行病。缺乏必要的解毒剂,如依地酸钙钠和甲吡唑,这一直是有效治疗中毒患者的主要问题。尽管众所周知,中毒和药物过量在一些发展中国家构成了医院就诊的重要比例,但中毒患者的临床毒理学教育和医疗护理却缺乏。因此,政策制定者和卫生当局应该认识到毒理学在临床医学中的重要性。伊朗卫生部、医疗保健和医学教育部应为医学生开设临床毒理学课程;建立有效的国家毒物信息和控制中心,推进临床毒理学服务,为中毒患者进行适当管理,以改善公众健康和整体卫生政策目标。