Department of Thoracic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Surgery, Columbia University Medical Center, New York, New York.
Department of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Ann Thorac Surg. 2020 Apr;109(4):1047-1053. doi: 10.1016/j.athoracsur.2019.10.069. Epub 2019 Dec 18.
Single-site, dual-lumen venovenous extracorporeal membrane oxygenation ECMO) facilitates mobilization, reduces recirculation, and mitigates insertion and infectious risks of an additional access site. This study reports the experience with a bicaval dual-lumen cannula that comprises a robust physical design allowing for easy and safe cannulation, precise positioning and monitoring, and appropriate physiologic support for patients with acute respiratory failure.
Statistical analysis was performed from data gathered retrospectively from the electronic medical records of 20 adult patients who were cannulated for ECMO with this bicaval dual-lumen cannula from August 2018 through May 2019.
Gas exchange and blood flow were optimized in all patients after cannulation (median pH, 7.42 [interquartile range {IQR}, 7.39, 7.44], ratio of arterial partial pressure of oxygen to fraction of inspired oxygen, 186.5 [Pao:Fio, 116.5, 247.0]; pump flow, 3.9 L/min [IQR, 3.1, 4.3]). Eleven patients (55%) were able to be freed from mechanical ventilation after cannulation, 9 (45%) patients underwent a tracheostomy procedure while undergoing ECMO, and no patients required reintubation. No morbidity or mortality was related to the cannulation strategy or the catheter. Two patients required cannula repositioning. Survival to decannulation was 90%, and survival to hospital discharge was 80%.
The bicaval dual-lumen cannula maintains the advantages of upper body single-site configuration to provide the adjunctive respiratory support necessary to facilitate awakening and rehabilitation while minimizing the use of invasive mechanical ventilation. This cannula introduces design qualities that may offer advantages for acute respiratory failure requiring venovenous ECMO.
单部位双腔静脉-静脉体外膜肺氧合(ECMO)便于移动,减少再循环,并降低了额外入路的插入和感染风险。本研究报告了一种双腔双腔套管的经验,该套管具有强大的物理设计,可实现安全、精准的置管和监测,并为急性呼吸衰竭患者提供适当的生理支持。
从 2018 年 8 月至 2019 年 5 月期间使用该双腔双腔套管进行 ECMO 置管的 20 例成年患者的电子病历中回顾性收集数据进行统计分析。
所有患者置管后(中位数 pH 值 7.42[四分位距 {IQR},7.39,7.44],动脉血氧分压与吸入氧分数比 186.5[Pao:Fio,116.5,247.0],泵流量 3.9 L/min[IQR,3.1,4.3])均实现了气体交换和血流的优化。置管后 11 例(55%)患者成功脱离机械通气,9 例(45%)患者在接受 ECMO 的同时行气管切开术,无一例患者需要重新插管。置管策略或导管与任何发病率或死亡率均无关。两名患者需要重新定位导管。脱机生存率为 90%,出院生存率为 80%。
双腔双腔套管保留了上半身单部位配置的优势,提供了必要的辅助呼吸支持,以促进觉醒和康复,同时最大限度地减少有创机械通气的使用。该套管引入的设计特性可能为需要静脉-静脉 ECMO 的急性呼吸衰竭提供优势。