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早期胆囊造瘘术治疗重症急性胆囊炎患者的结局

Outcomes of Patients Treated With Upfront Cholecystostomy for Severe Acute Cholecystitis.

作者信息

De Geus Thea, Moriarty Heather K, Waters Peadar S, O'Reilly Michael K, Lawler Leo, Geoghegan Tony, Conneely John C, McEntee Gerry, Farrelly Cormac

机构信息

Departments of Radiology.

Hepatobiliary Surgery, Mater Misericordiae University Hospital, Dublin, Ireland.

出版信息

Surg Laparosc Endosc Percutan Tech. 2020 Feb;30(1):79-84. doi: 10.1097/SLE.0000000000000747.

Abstract

INTRODUCTION

Percutaneous cholecystostomy tube (PCT) placement is a treatment method for acute cholecystitis, both in adult patients unsuitable for surgery and those failing to improve with conservative management. The purpose of this study was to assess the outcomes of patients undergoing cholecystostomy.

MATERIALS AND METHODS

A review of consecutive patients who underwent PCT insertion over a 10-year period was performed. Outcomes assessed included cholecystostomy dwell time, tubogram requirement, cholecystostomy reinsertion, cholecystectomy, bile leaks, and mortality.

RESULTS

One hundred eight patients (77 male individuals, 31 female individuals) were included. The mean age was 70 years (range: 29 to 93 y). A total of 89 transhepatic and 19 transperitoneal PCTs were inserted. Fifty-nine patients (55%) had a subsequent tubogram to assess cystic duct patency or catheter position. Mean catheter dwell time was 17 days (range: 1 to 154 d). Eleven (10%) required PCT reinsertion. Time to reinsertion ranged from 2 to 163 days (mean=38 d). Fifty-three patients (50%) had no further biliary intervention after removal of the cholecystostomy catheter. One patient required subsequent drainage of a hepatic abscess, and another developed a biloma. Thirty-two patients (30%) underwent cholecystectomy (66% laparoscopic, 34% open). Thirty-day mortality after PCT insertion was 8.3%. Twenty patients (19%) died of non-cholecystostomy-related illness during the 10-year follow-up period.

CONCLUSIONS

Cholecystostomy is an important treatment method of acute cholecystitis as a bridge to cholecystectomy or as an alternative definitive treatment option in those unsuitable for surgery. A tubogram is not always necessary before tube removal. Cholecystostomy tubes can be removed safely with little risk of bile leak if patients are clinically well, and clean-appearing bile is draining.

摘要

引言

经皮胆囊造瘘管(PCT)置入术是治疗急性胆囊炎的一种方法,适用于不适合手术的成年患者以及经保守治疗后病情未改善的患者。本研究的目的是评估接受胆囊造瘘术患者的治疗结果。

材料与方法

对连续10年接受PCT置入术的患者进行回顾性研究。评估的结果包括胆囊造瘘管留置时间、造影检查需求、胆囊造瘘管重新置入、胆囊切除术、胆漏和死亡率。

结果

共纳入108例患者(77例男性,31例女性)。平均年龄为70岁(范围:29至93岁)。共置入89根经肝和19根经腹PCT。59例患者(55%)随后进行了造影检查以评估胆囊管通畅情况或导管位置。平均导管留置时间为17天(范围:1至154天)。11例患者(10%)需要重新置入PCT。重新置入的时间范围为2至163天(平均=38天)。53例患者(50%)在拔除胆囊造瘘管后未进行进一步的胆道干预。1例患者随后需要引流肝脓肿,另1例患者出现胆汁瘤。32例患者(30%)接受了胆囊切除术(66%为腹腔镜手术,34%为开放手术)。PCT置入术后30天死亡率为8.3%。在10年随访期间,20例患者(19%)死于与胆囊造瘘术无关的疾病。

结论

胆囊造瘘术是急性胆囊炎的一种重要治疗方法,可作为胆囊切除术的桥梁,或作为不适合手术患者的替代确定性治疗选择。拔管前不一定需要进行造影检查。如果患者临床状况良好且引流胆汁外观清洁,胆囊造瘘管可以安全拔除,胆漏风险很小。

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