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3D 模型辅助下顺式维甲酸治疗后肾母细胞瘤病行零缺血腹腔镜肾部分切除术。

3D Model Facilitated Zero-Ischemia Laparoscopic Nephron Sparing Resection in Nephroblastomatosis Following the Addition of Cis-Retinoic Acid.

机构信息

Birmingham Children's Hospital, Birmingham, United Kingdom.

出版信息

Urology. 2020 Apr;138:148-151. doi: 10.1016/j.urology.2019.12.012. Epub 2019 Dec 27.

Abstract

There are limited reports of laparoscopic nephron sparing surgery (LNSS) in children and none where a 3D model facilitated oncological resection. There are also limited reports discussing the use of cis-retinoic acid in bilateral diffuse hyperplastic perilobar nephrogenic rests (DHPLNR). We report the first case of a 3D model facilitated zero-ischemia LNSS in children and the first following treatment with cis-retinoic acid. The patient was a 3-year-old girl with bilateral DHPLNR who had recurrent disease following standard therapy. She had suspicious lesions in the upper pole of the left kidney. Both were completely excised and histologically described as hyperplastic nephrogenic rests.

摘要

目前仅有有限的关于儿童腹腔镜肾部分切除术(LNSS)的报告,且没有报告涉及使用 3D 模型来辅助进行肿瘤学切除。也仅有有限的报告讨论了 cis-视黄酸在双侧弥漫性增生性副肾叶肾母细胞瘤残余(DHPLNR)中的应用。我们报告了首例儿童 3D 模型辅助无缺血 LNSS 的病例,也是首例 cis-视黄酸治疗后的病例。该患者为 3 岁女孩,双侧均患有 DHPLNR,经标准治疗后复发。她的左肾上级有可疑病变。这两个病变均被完全切除,组织学描述为增生性肾母细胞瘤残余。

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