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庞塞蒂方法治疗后特发性马蹄内翻足早期复发的相关因素

Factors Related to Early Recurrence of Idiopathic Clubfoot Post the Ponseti Method.

作者信息

Limpaphayom N, Sailohit P

机构信息

Department of Orthopaedics, Chulalongkorn University, Bangkok, Thailand.

Department of Orthopaedics, Police General Hospital, Bangkok, Thailand.

出版信息

Malays Orthop J. 2019 Nov;13(3):28-33. doi: 10.5704/MOJ.1911.005.

Abstract

Idiopathic clubfoot or congenital talipes equinovarus (CTEV) is managed by the Ponseti method worldwide; however, the recurrence of the deformity is a challenging problem. The purpose was to review the factors associated with early recurrence of CTEV post the Ponseti method. During 2011-2016, 34 infants with 52 CTEV, who underwent the Ponseti method and a minimum follow-up period of six months, were reviewed. Twenty-two infants (65%) were male, and 18 infants (53%) had bilateral CTEV. Recurrence of CTEV was defined as a reappearance of at least one of the four components of the deformity. The association between recurrence and factors, including age, gender, bilaterality, family geography, type of principal caregiver, severity at presentation, centre where the Ponseti method was initiated, compliance to foot abduction brace (FAB), practice of stretching exercise, type of FAB, and complications of casting, were evaluated using univariate logistic regression analysis. The median age at initiation of the treatment was 3.4 (IQR; 2.1-12.6) weeks. A median of six (range; 3-12) casts were required. Tenotomy was performed in 32/34 (94%) of cases. Recurrence occurred in 14/52 feet (27%) at an average follow-up period of 2.3±1.1 years. Non-compliance to FAB protocol began at an average age of 11.2±6.5 months, and significantly increased the risk of recurrence during the weaning phase [OR (95%CI)=8.4 (1.2-92.4), p=0.03]. Other factors were not associated with the recurrence. Non-compliance to FAB occurred early during the treatment and related to a risk of recurrence of CTEV. Physicians should encourage the parents and/or guardians to follow the protocol to decrease the risk of recurrence.

摘要

在全球范围内,特发性马蹄内翻足或先天性马蹄内翻足(CTEV)采用庞塞蒂方法进行治疗;然而,畸形复发是一个具有挑战性的问题。本研究旨在回顾与庞塞蒂方法治疗后CTEV早期复发相关的因素。在2011年至2016年期间,对34例患有52只CTEV的婴儿进行了回顾性研究,这些婴儿均接受了庞塞蒂方法治疗,且随访期至少为6个月。22例婴儿(65%)为男性,18例婴儿(53%)患有双侧CTEV。CTEV复发定义为畸形的四个组成部分中至少有一个再次出现。采用单因素逻辑回归分析评估复发与年龄、性别、双侧性、家庭地理位置、主要照顾者类型、就诊时的严重程度、开始庞塞蒂方法治疗的中心、对足外展支具(FAB)的依从性、伸展运动的实施情况、FAB类型以及石膏固定并发症等因素之间的关联。治疗开始时的中位年龄为3.4(四分位间距;2.1 - 12.6)周。平均需要6(范围;3 - 12)次石膏固定。34例中的32例(94%)进行了跟腱切断术。在平均2.3±1.1年的随访期内,14/52只足(27%)出现复发。对FAB方案的不依从平均始于11.2±6.5个月龄,并且在断奶阶段显著增加了复发风险[比值比(95%置信区间)=8.4(1.2 - 92.4),p = 0.03]。其他因素与复发无关。对FAB的不依从在治疗早期出现,并且与CTEV复发风险相关。医生应鼓励父母和/或监护人遵循方案以降低复发风险。

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